Institute for Physics

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    Comparative analysis of different nuclear medicine techniques in evaluation of renal function
    (VIA MEDICA Journals, 2023)
    Aleksandra Peshevska, Tanja Makazlieva, Venjamin Majstorov, Lambe Barandovski, Irena Rambabova-Bushljetik, Daniela Miladinova
    Introduction: Nuclear medicine (NM) methods play an important role in the evaluation of renal function in a wide range of clinical indications. The aim of our study was to evaluate the correlation between measured GFR (mGFR) obtained by the three-plasma sample slope-intercept NM method (TPSM) — reference method vs. estimated GFR (eGFR) using Fleming’s single plasma sample method (SPSM) at 120 min, 180 min, and 240 min and correlation of reference method with eGFR with camera-based Gates’ protocol. Material and methods: A total of 82 subjects (33 male/49 female) with a mean age of 54.87 ± 15.65 years were included and mGFR value was obtained by the three-plasma sample slope-intercept NM method and eGFR was obtained with Fleming’s single sample method. eGFR was also quantified with the camera-based Gates’ protocol after i.v. application of [99mTc]Tc-DTPA. Results: Our study revealed a very strong positive significant correlation between all three SPSMs with the TPSM as the reference method. Between the Gates’ method and the TPSM in the group of patients with mGFR ≥ 61–84 mL/min/1.73 m2 and mGFR ≥ 84 mL/min/1.73 m2, a moderate positive statistically significant correlation was obtained. Conclusions: The SPSM method shows a very strong correlation with the reference and low bias in all three groups of patients and can be routinely used for GFR estimation.
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    Spatial distribution and isotopic signatures of N and C in mosses across Europe
    (Elsevier, 2025-01-01)
    Sheila Izquieta-Rojano, Yasser Morera-Gómez, David Elustondo, Esther Lasheras, Carolina Santamaría, Julen Torrens-Baile, Renate Alber, Lambe Barandovski, Mahmut Coşkun, Munevver Coskun, Helena Danielsson, Ludwig De Temmerman, Harry Harmens, Zvonka Jeran, Sébastien Leblond, Javier Martínez-Abaigar, Encarnación Núñez-Olivera, Roland Pesch, Juha Piispanen, Gerhard Soja, Zdravko Spiric, Trajče Stafilov, Lotti Thöni, Jesús Miguel Santamaría
    The accumulation of nitrogen (N) in moss tissue has proven to be a reliable marker of increasing N deposition. However, this measurement does not offer additional data about the origin of pollution. In this respect, the analysis of the N isotopic ratios might be a helpful tool in providing supplementary information about the nature of the nitrogenous species in biomonitoring surveys. Furthermore, isotopic signatures have been extensively used in the study of N and carbon (C) biogeochemical cycles. The main purpose of this study was to determine N and C elemental contents and their stable isotopes in mosses to investigate atmospheric pollution patterns across Europe. We aimed at identifying the main N polluted areas and evaluating the potential use of isotopic signatures in the attribution of pollution sources at a regional scale. With these objectives in mind, >1300 samples from 15 countries from Europe, all of them participants of the ICP-Vegetation programme 2005–2006, were analyzed for their C and N contents and δ15N and δ13C. The results were compared to those derived from EMEP model, which provided modeled deposition and emission data, as well as to the predominant land uses at the sampling sites (based on CORINE Land Cover). This evaluation suggests that additional measurements of stable C and N isotopes in mosses could be a valuable tool in European environmental surveys. Such measurements not only provide useful information for identifying probable pollution sources but also enable the quantification of their contributions, serving as biological indicators of significant environmental processes. This study presents the first quantitative assessment of major atmospheric nitrogen (N) sources based on stable isotope analysis on a European scale, establishing a framework for evaluating historical changes in N across the region.
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    Mercury Pollution in Terrestrial Ecosystems of North Macedonia: Insights from an 18-Year Moss Biomonitoring Programme
    (MDPI, 2025-12-22)
    Katerina Bačeva Andonovska, Robert Šajn, Jasminka Alijagić, Trajče Stafilov, Lambe Barandovski
    Moss biomonitoring was conducted in 2002, 2005, 2010, 2015 and 2020 to evaluate atmospheric mercury (Hg) deposition across N. Macedonia as part of a comprehensive survey of potentially toxic elements (PTEs). More than 70 samples of the dominant moss species Hypnum cupressiforme and Homalothecium lutescens were collected during the summer field campaigns. Mercury concentrations were determined using cold vapour atomic absorption spectrometry and inductively coupled plasma mass spectrometry (ICP-MS). The results revealed marked temporal fluctuations: median Hg content increased from 56 µg/kg in 2002 to 68 µg/kg in 2005, peaked at 93 µg/kg in 2010, then decreased to 84 µg/kg in 2015, and further to 52 µg/kg in 2020. Over the study period, Hg concentrations ranged from 10 to 595 µg/kg, with the highest variability observed in 2010. Spatial distribution maps and regional comparisons indicate that elevated Hg contents correspond predominantly to anthropogenic sources, particularly in industrialised zones and regions affected by mining and metallurgical activities. The 2020 dataset shows a significantly lower median value (52 µg/kg) compared to previous surveys, indicating a slight improvement in air quality, although local hotspots persist. These results highlight the importance of long-term moss biomonitoring as a cost-effective approach for tracking atmospheric mercury trends and informing national environmental policy.
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    Spin states of X-complex asteroids in the inner main belt -- I. Investigating the Athor and Zita collisional families
    (2024-10)
    D. Athanasopoulos
    ;
    J. Hanuš
    ;
    C. Avdellidou
    ;
    G. van Belle
    ;
    A. Ferrero
    The aim of our study is to characterise the spin states of the members of the Athor and Zita collisional families and test whether these members have a spin distribution consistent with a common origin from the break up of their respective family parent asteroids. Our method is based on the asteroid family evolution, which indicates that there should be a statistical predominance of retrograde-rotating asteroids on the inward side of family's V-shape, and prograde-rotating asteroids on the outward side. We used photometric data from our campaign and the literature in order to reveal the spin states of the asteroids belonging to these families. We combined dense and sparse photometric data in order to construct lightcurves; we performed the lightcurve inversion method to estimate the sidereal period, spin axis and convex shape of several family members. We obtained 34 new asteroid models for Athor family members and 17 for Zita family members. Along with the literature and revised models, the Athor family contains 60% of retrograde asteroids on the inward side and, 76% of prograde asteroids on the outward side. We also found that the Zita family exhibits 80% of retrograde asteroids on the inward side and an equal amount of prograde and retrograde rotators on the outward side. However, when we applied Kernel density estimation, we also found a clear peak for prograde asteroids on the outward side, as expected from the theory. The spin states of these asteroids validate the existence of both families, with the Athor family exhibiting a stronger signature for the presence of retrograde-rotating and prograde-rotating asteroids on the inner and outer side of the family, respectively. Our work provides an independent confirmation and characterisation of these very old families, whose presence and characteristics offer constraints for theories and models of the Solar System's evolution.
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    Access to diagnostic imaging and radiotherapy technologies for patients with cancer in the Baltic countries, eastern Europe, central Asia, and the Caucasus: a comprehensive …
    (The Lancet, 2024-11)
    Manjit Dosanjh, Vesna Gershan, Eugenia C Wendling, Jamal S Khader, Taofeeq A Ige, Mimoza Ristova, Richard Hugtenburg, Petya Georgieva, C Norman Coleman, David A Pistenmaa, Gohar H Hovhannisyan, Tatul Saghatelyan, ... et.al.
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    Effect of vegetable fat on the texture, colour and sensory properties of Macedonian white brined cheese
    (Croatian Dairy Union, 2020-12-14)
    Sulejmani, Erhan
    ;
    Beqiri, Lavdrim
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    Popeski-Dimovski, Riste
    <jats:p>This study aimed to investigate the influence of substitution of milk fat with palm fat on the composition, yield and technological quality of White cheese, a Macedonian traditional cheese. In this study, full-fat white brined cheese was used as a control sample (WC), while experimental cheeses were prepared from cow milk with vegetable fat (WV) addition and low-fat cheese (WL), respectively. The cheeses have been analysed for physicochemical (acidity, pH, fat, fat acidity, protein), instrumental texture and colour properties (L, a, b) as well as the sensory properties after 1, 20 and 60 days. WV cheeses showed a significantly (P<0.05) lower degree of pH and higher titratable acidity than the WC and WL cheese samples. Cheese that contained vegetable fat showed lower degrees of lipolysis, as assessed by the acid-degree value and received significantly (P<0.05) better appearance, highest hardness value (5226.98 N) and cheese yield scores compared to other samples.</jats:p>
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    Tunable high-Q resonator by general impedance converter
    (AIP Publishing, 2021-02-01)
    Mifune, Toshiro
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    Mishonov, Todor M.
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    Serafimov, Nikola S.
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    Dimitrova, Iglika M.
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    Popeski-Dimovski, Riste
    <jats:p>A tunable high-Q resonator is performed in the schematics of the General Impedance Converter (GIC). In the framework of frequency dependent open-loop gain of operational amplifiers, a general formula of the frequency dependence of the impedance of GIC is derived. The explicit formulas for the resonance frequency and Q-factor include as an immanent parameter the crossover frequency of the operational amplifier. Voltage measurements of GIC with a lock-in amplifier perfectly agree with the derived formulas.</jats:p>
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    Lightcurve analysis of asteroid 15691 Maslov using NAO Rozhen observations and sparse data
    (Institute of Astronomy and NAO 72 Tsarigradsko Shosse Blvd., BGN-1784 Sofia, Bulgaria, 2023)
    Vchkova Bebekovska, Elena
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    Boeva, Svetlana
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    Petrov, Blagovest
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    Borisov, Galin