Ве молиме користете го овој идентификатор да го цитирате или поврзете овој запис:
http://hdl.handle.net/20.500.12188/3535
Наслов: | Effect of laser on TNF-alpha expression in inflamed human gingival tissue | Authors: | Pesevska S Nakova M Gjorgoski I Angelov N Ivanovski K Nares S Andreana S |
Issue Date: | мар-2012 | Publisher: | Springer Science and Business Media LLC | Journal: | Lasers in medical science | Abstract: | This study sought to evaluate the effect of low-level laser treatment combined with scaling and root planing (SRP) on gingival tissue levels of TNF-alpha in subjects with periodontal disease. Eighty gingival papilla biopsy samples were obtained from 60 patients diagnosed with chronic advanced periodontitis; randomly assigned to three treatment groups (n = 20), as well as 20 subjects with no periodontal disease (group A). Group B received SRP on a single quadrant/day for four consecutive days. On day 5, all quadrants were rescaled. Groups C and D received the same treatment as group B plus laser application with the low-level diode laser (630-670 nm, 1.875 J/cm(2)) for five and ten consecutive days, respectively. Papilla biopsies were obtained from subjects and evaluated by ELISA for levels of TNF-alpha. The values in the control group were 5.2 ± 3.21 pg/mg and baseline values for the examined groups were 46.01 ± 16.69. Significantly decreased level of TNF-alpha for groups C and D was found after treatment, while group B demonstrated reduction of TNF-alpha of 31.34%. The results of this study show suppression of TNF-alpha in gingival tissue after low-level laser treatment as adjunct to SRP. Data may suggest beneficial anti-inflammatory effects of the laser treatment when used as adjunctive periodontal treatment. | URI: | http://hdl.handle.net/20.500.12188/3535 | DOI: | 10.1007/s10103-011-0898-x |
Appears in Collections: | Faculty of Dentistry: Articles |
Прикажи целосна запис
Записите во DSpace се заштитени со авторски права, со сите права задржани, освен ако не е поинаку наведено.