Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12188/3535
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Pesevska S | en_US |
dc.contributor.author | Nakova M | en_US |
dc.contributor.author | Gjorgoski I | en_US |
dc.contributor.author | Angelov N | en_US |
dc.contributor.author | Ivanovski K | en_US |
dc.contributor.author | Nares S | en_US |
dc.contributor.author | Andreana S | en_US |
dc.date.accessioned | 2019-10-22T13:19:45Z | - |
dc.date.available | 2019-10-22T13:19:45Z | - |
dc.date.issued | 2012-03 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.12188/3535 | - |
dc.description.abstract | This study sought to evaluate the effect of low-level laser treatment combined with scaling and root planing (SRP) on gingival tissue levels of TNF-alpha in subjects with periodontal disease. Eighty gingival papilla biopsy samples were obtained from 60 patients diagnosed with chronic advanced periodontitis; randomly assigned to three treatment groups (n = 20), as well as 20 subjects with no periodontal disease (group A). Group B received SRP on a single quadrant/day for four consecutive days. On day 5, all quadrants were rescaled. Groups C and D received the same treatment as group B plus laser application with the low-level diode laser (630-670 nm, 1.875 J/cm(2)) for five and ten consecutive days, respectively. Papilla biopsies were obtained from subjects and evaluated by ELISA for levels of TNF-alpha. The values in the control group were 5.2 ± 3.21 pg/mg and baseline values for the examined groups were 46.01 ± 16.69. Significantly decreased level of TNF-alpha for groups C and D was found after treatment, while group B demonstrated reduction of TNF-alpha of 31.34%. The results of this study show suppression of TNF-alpha in gingival tissue after low-level laser treatment as adjunct to SRP. Data may suggest beneficial anti-inflammatory effects of the laser treatment when used as adjunctive periodontal treatment. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Springer Science and Business Media LLC | en_US |
dc.relation.ispartof | Lasers in medical science | en_US |
dc.title | Effect of laser on TNF-alpha expression in inflamed human gingival tissue | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1007/s10103-011-0898-x | - |
dc.identifier.url | http://link.springer.com/content/pdf/10.1007/s10103-011-0898-x.pdf | - |
dc.identifier.url | http://link.springer.com/article/10.1007/s10103-011-0898-x/fulltext.html | - |
dc.identifier.url | http://link.springer.com/content/pdf/10.1007/s10103-011-0898-x | - |
dc.identifier.volume | 27 | - |
dc.identifier.issue | 2 | - |
item.grantfulltext | none | - |
item.fulltext | No Fulltext | - |
Appears in Collections: | Faculty of Dentistry: Articles |
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