Faculty of Natural Sciences and Mathematics
Parent Organisation
City
Skopje
735 results
Filters
Settings
Now showing 1 - 10 of 735
- Some of the metrics are blocked by yourconsent settings
Item type:Publication, Inflammatory and oxidative stress markers in intracerebral hemorrhage: Relevance as prognostic markers for quantification of the edema volume(Wiley, 2023-03); ; We aimed to analyze the inflammatory and oxidative stress (OS) markers after intracerebral hemorrhage (ICH) and their temporal changes, interaction effects, and prognostic values as biomarkers for the prediction of the edema volume. Our prospective, longitudinal study included a cohort group of 73 conservatively treated patients with ICH, without hematoma expansion or intraventricular bleeding, which were initialized with the same treatment and provided with the same in-hospital care during the disease course. Study procedures included multilevel comprehensive analyses of clinical and neuroimaging data, aligned with the exploration of 19 inflammatory and five OS markers. White blood cells (WBC), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), neutrophilia, and lymphopenia peaked 3 days post-ICH, and they showed much stronger correlations with clinical and neuroimaging variables, when compared to the admission values. An intricate interplay among inflammatory (WBC, CRP, neutrophils, neutrophil-to-lymphocyte ratio [NLR], interleukin (IL)-6, and IL-10) and OS mechanisms (catalase activity and advanced oxidation protein products [AOPP]) was detected operating 3-days post-ICH, being assessed as relevant for prediction of the edema. The overall results suggested complex pathology of formation of post-ICH edema, via: (A) Not additive, but statistically significant synergistic interactions between CRP-ESR, neutrophils-CRP, and neutrophils-IL-6 as drivers for the edema formation; (B) Significant antagonistic effect of high protein oxidation on the CRP-edema dependence, suggesting a mechanism of potential OS-CRP negative feedback loop and redox inactivation of CRP. The final multiple regression model separated the third-day variables NLR, CRP × AOPP, and WBC, as significant prognostic biomarkers for the prediction of the edema volume, with NLR being associated with the highest effect size. Our developed mathematical equation with 3D modeling for prediction and quantification of the edema volume might be beneficial for taking timely adequate strategies for prevention of delayed neurological deteriorations. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Finite-Temperature Single Molecule Vibrational Dynamics from Combined Density Functional Tight Binding Extended Lagrangian Dynamics Simulations and Time Series Analysis(BULGARIAN ACADEMY OF SCIENCES, 2020-12-31); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Некои алгоритми за решавање на задачата на патувачкиот трговец(Природно-математички факултет, Скопје, 2017-09-23)Задачата на патувачкиот трговец (Traveling Salesman Problem - TSP) е една од најистражуваните комбинаторни оптимизациони задачи. Нејзината формулација е многу едноставна: Патувачкиот трговец треба да ја најде најоптималната (најкратка или најефтина) тура низ n дадени града. Но, и покрај едноставната формулација, нејзиното решавање сè уште претставува предизвик. Оваа задача е во тесна врска со еден од милениумските нерешени проблеми. Ќе разгледаме неколку примени на задачата на патувачкиот трговец, како и неколку алгоритми за нејзино решавање. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Amplitude death and chimera patterns in complex networks with time delays(Russian Academy of Sciences, Institute of Applied Physics, Nizhny Novgorod, 2017); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Phenolics and mineral content in bilberry and bog bilberry from Macedonia(Informa UK Limited, 2017-07-18); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Topical gel with ethyl cellulose based microsponges loaded with clindamycin hydrochloride for acne treatment(Springer Science and Business Media LLC, 2020-06-10) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Comment on “Spectator Ions ARE Important! A Kinetic Study of the Copper−Aluminum Displacement Reaction”(American Chemical Society (ACS), 2010-11-03); Petruševski, Vladimir M. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Examination of in-cloud sulfate chemistry using a different model initialization(Springer Nature, 2018-12-13); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Математичко моделирање и задачи на Ферми во наставата по математика(Природно-математички факултет, Скопје, 2017-09-23) - Some of the metrics are blocked by yourconsent settings
Item type:Publication,