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Language: search.filters.language.EnglishSubject: search.filters.subject.Breast density

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    Breast Glandularity Distribution and Refining the Mean Glandular Dose Estimates in Digital Mammography
    (Ovid Technologies (Wolters Kluwer Health), 2025-10)
    Arifi, Mirjeta Mediji
    ;
    Background: In mammography, radiation dose is typically expressed as the mean glandular dose (MGD), which represents the dose delivered to the glandular tissue of the breast. Materials and Methods: This study compares MGD estimates obtained using three different methodologies: (I) MGD-Dance-Laboratory for Individualized Breast Radiodensity Assessment (LIBRA) – Calculated manually for each patient using Dance’s formula, incorporating mammographic breast density values derived from the LIBRA application, thereby replacing Dance’s standard glandularity assumption with image-specific values; (II) MGD-Dance – Calculated using Dance’s formula with the conventional assumption of 50% glandularity; (III) MGD-Displayed – Extracted directly from the Digital Imaging and Communication in Medicine header of each mammogram. Results: A total of 688 anonymized mammograms from 172 women undergoing routine screening were analyzed, with complete technical and patient-related data. The mean MGD values obtained by the three methods were: MGD-Dance-LIBRA: 2.97 mGy; MGD-Dance: 2.78 mGy; and MGD-Displayed: 2.81 mGy. The average glandularity across the dataset was estimated at 14%. A strong correlation was observed between MGD-Dance and MGD-Dance-LIBRA values (R² =0.9865). The refined dose estimation using image-specific glandularity from LIBRA consistently produced slightly higher values compared to the standard Dance method, highlighting the impact of the commonly assumed 50% glandularity, which overestimates the true average density. Conclusions: Incorporating individualized breast density estimates from the LIBRA application into Dance’s formula provides a more refined and accurate method for calculating MGD in digital mammography.