Faculty of Medicine

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    Item type:Publication,
    VARICELLA ZOSTER VIRUS AND MENINGITIS IN IMMUNOCOMPETENT PATIENT - CASE REPORT
    (Peytchinski Publishing Ltd., Pleven, Bulgaria, 2024-10)
    Stojanoska, Tatjana
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    Varicella zoster virus reactivation, also known as herpes zoster is common in older adults and immunocompromised individuals and often causes a painful, vesicular rash limited to a dermatomal distribution. On occasion, it can lead to various neurological complications as well. Meningitis caused by varicella zoster virus infection is uncommon in immunocompetent patients. We report the case of a 49-year-old male patient that presented with a one-week history of persistent headache that did not resolve with analgesics. He was previously healthy and immunocompetent, with a history of chickenpox in childhood. The CSF PCR analysis revealed a VZV infection causing acute aseptic meningitis with no shingles rash eruption on physical examination. Intravenous treatment with Acyclovir was started and following a three-week treatment course, the patient was discharged in good general condition with normal CSF results.