VARICELLA ZOSTER VIRUS AND MENINGITIS IN IMMUNOCOMPETENT PATIENT - CASE REPORT
Journal
Journal of IMAB
Date Issued
2024-10
Author(s)
Stojanoska, Tatjana
Rangelov, Goran
Cana, Fadil
Dimitrova, Emilija
Milosavljevikj, Ane
DOI
10.5272/jimab.2024v30Supplement-14-34
Abstract
Varicella zoster virus reactivation, also known as herpes zoster is common in older adults and
immunocompromised individuals and often causes a painful, vesicular rash limited to a
dermatomal distribution. On occasion, it can lead to various neurological complications as well.
Meningitis caused by varicella zoster virus infection is uncommon in immunocompetent
patients. We report the case of a 49-year-old male patient that presented with a one-week history
of persistent headache that did not resolve with analgesics. He was previously healthy and
immunocompetent, with a history of chickenpox in childhood. The CSF PCR analysis revealed a
VZV infection causing acute aseptic meningitis with no shingles rash eruption on physical
examination. Intravenous treatment with Acyclovir was started and following a three-week
treatment course, the patient was discharged in good general condition with normal CSF results.
immunocompromised individuals and often causes a painful, vesicular rash limited to a
dermatomal distribution. On occasion, it can lead to various neurological complications as well.
Meningitis caused by varicella zoster virus infection is uncommon in immunocompetent
patients. We report the case of a 49-year-old male patient that presented with a one-week history
of persistent headache that did not resolve with analgesics. He was previously healthy and
immunocompetent, with a history of chickenpox in childhood. The CSF PCR analysis revealed a
VZV infection causing acute aseptic meningitis with no shingles rash eruption on physical
examination. Intravenous treatment with Acyclovir was started and following a three-week
treatment course, the patient was discharged in good general condition with normal CSF results.
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