Faculty of Medicine
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Item type:Publication, PREVALENCE OF ANEMIA IN PATIENTS WITH MISSED ABORTION(Македонско лекарско друштво = Macedonian medical association, 2025-09); ; ; Bekim DikaIntroduction: Miscarriage (abortion), 85% of which may happen during the first trimester, is one of the most common adverse pregnancy outcomes. Almost half of miscarriages are a consequence of chromosomal abnormalities. The risk factors include advanced maternal age, comorbidities (obesity, diabetes, hypertension), previous miscarriages, smoking and inappropriate nutritional status. Anaemia is the most prominent haematological abnormality during gestation and it is a global health problem affecting nearly half of all pregnant women. Anaemia has been linked to a higher risk of adverse outcomes, including maternal mortality, stillbirth, preterm births, small-for-gestational-age (SGA). World Health Organization has defined anaemia in pregnancy as the haemoglobin (Hgb) concentration of less than 110g/L. The primary cause of anemia during pregnancy is iron deficiency secondary to chronic inadequate dietary intake and menstruation, heightened by the physiologic demands of the fetus and maternal blood volume expansion during pregnancy. The aim of our study was to determine the prevalence of anemia in women with missed abortion in the first trimester of pregnancy, who are not bleeding. Material and methods: In 80 patients with missed abortion in the first trimester of pregnancy, we determined the level of Hgb in capillary blood. Results: In 31 women (38,8%), we detected anemia (the level of Hgb below 110g/L), and 7 of them (8,8% of the total number of women) had a severe anemia with Hgb levels below 90 g/L. As pregnancy progresses, we expect this prevalence to increase. Conclusion: We want to emphasize that a large percentage of women are anemic even preconceptually and early in pregnancy, so if it is not detected and treated, the severity of anemia worsens as the pregnancy progresses. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, ANEMIA IN PREGNANCY AND RISK FACTORS(Македонско лекарско друштво = Macedonian medical association, 2025-09); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Postpartum Juvenile Granulosa Cell Tumor: A Case Report(Austin Publishing Group, 2023-01-25); ; ; ; Akiku Kamberi, ElmedinaGranulosa Cell Tumors (GCTs) are extremely rare, sex cord-stromal tumors constituting only 1% to 2% of all ovarian malignancies. On the basis of age of onset and pathohistological characteristics, these tumors are subdivided into two distinct forms, the adult type (AGCT) and the juvenile type (JGCT), representing 95% and 5% of the tumors, respectively. Compared to the adult type, which is more common in the fifth decade, JGCT is rarely seen and the majority (90%) is reported in prepubertal individuals or those aged less than 30 years. We report an interesting case of a 24-years old woman with enormous ovarian juvenile granulosa cell tumor of the right ovary. Considering all the anamnestic data and ultrasound reports before and during the first pregnancy, where there has been no evidence for the presence of any tumor, we came to conclusion that the tumor grew rapidly during the first year since delivery. Maybe the tumor was present during the pregnancy or even before, but most probably it was not noticed because it small initial size or it was masked by the growing uterus at ultrasound. The first data for the tumor existence is 3 months before the surgical treatment. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Red Blood Cell Variables in Children and Adolescents regarding the Age and Sex(Tehran University of Medical Sciences, 2019-04); ; ; Daniela Shukova StojmanovaBackground: This study aimed to assess the basic red blood cell variables and hematological indices in children and adolescents and analyze the differences regarding age and sex. Methods: Overall, 320 young participants, age 8 to 18 years, were enrolled at Laboratory of sport’s medicine, Medical Faculty, Skopje during the 2016. Capillary blood samples were drawn and following hematologic parameters were measured: the red blood cell count (RBC), hemoglobin concentration (Hb), hematocrit level (Hct) and hematological indexes: mean corpuscular volume (MCV), mean hemoglobin concentration (MCH), mean corpuscular hemoglobin concentration (MCHC) and red cell distribution width (RDW). Results: RBC variables in male group showed high statistical level of significance between age different groups (P=0.001) for all studied parameters except MCHC (P=0.423) and RDW (P=0.174). ANOVA test and multivariate tests in female group showed that there was no significant difference for all hematological parameters between age different groups. Regarding the sex differences, male participants had significantly higher red blood count (P<0.001), hemoglobin content (P<0.001) and hematocrit (P<0.001). Conclusion: Hematological parameters in adolescent as inhomogeneous population are not quantified sufficiently, especially hematological indices. RBC variables, regardless of the age, differ very much between male and female subjects, in favor of the male subjects. Hematological indices were insignificantly higher in males. Regarding the age RBC variables showed significant inter-groups differences only within male adolescents. While with girls, ages span 8 to 18 yr, we did not find significant differences for most of the hematological variables. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Red blood cell variables, their inter-correlations and correlations with body mass components in boys aged 10-17 years(Turkish National Pediatric Society, 2020-01); ; ; Daniela Shukova StojmanovskaObjective of this study was to analyze the hematological parameters, their inter-correlation and their correlation with body composition components in young male adolescent subjects.One hundred and ninety (190) physically active male subjects, aged 10 to 17 years, mean age 13.37 4.5 years, were included in the study. Capillary blood was taken from all subjects and the following hematological parameters were measured: red blood cell count (RBC); hematocrit (Ht); hemoglobin mass (Hb) and hematological indices (MCV,MCH, MCHC).The body components derived from Matiegka anthropometric method were assessed: muscular mass (MM%), bone mass (BM%), body fat mass (BF%). The mean values (SD) for hematological parameters were RBC= 5.070.41 x 1012/l,Hb=14.241.24 g/dl, Hct=43.833.8%. Anthropometric characteristics were as follows: BMI was 20.26 3.27 kg /m2, relative muscular mass (MM%) was 53.18 3.19 %, bone mass (BM%) was 18.83 2.4% and body fat percent (BF%) was 15.19 2.64 %. Correlation’s analysis between hematological parameters and body composition showed moderate to strong correlation between RBC, Hb and Hctand all body components. The strongest correlations were found between Hb and Hct and the muscular mass (r= 0.60; r= 0.61) and the lean body mass (r= 0.59).The hematological parameters are positively associated with all body mass components, while the strongest correlations were found between hemoglobin levels and hematocrit and skeletal muscle mass and lean body mass. The knowing and understanding of the relationship between RBC variables and body composition parameters could be important in healthcare planning for children.