Faculty of Medicine
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Item type:Publication, Epidemiology and impact of frailty in patients with atrial fibrillation in Europe(Oxford University Press (OUP), 2022-08) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Evaluation of the causes of the neurotrauma(2004) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Epidemiology, Evaluation and Surgical Treatment of undescended Testis in North Macedonia in the Period from 2011 to 2020(Albanian Society for Trauma and Emergency Surgery, 2023-01-20); ; ; Coklevska Shuntov, NataliaBackground; Cryptorchidism or undescended testis (UDT) is one of the most common pediatric disorders of the male endocrine glands and the most common genital disorder identified at birth. The main reasons for treatment of cryptorchidism include increased risks of impairment of fertility potential, testicular malignancy, testis torsion, and/or associated inguinal hernia Material and Methods; The aim of this study is to show the epidemical distribution of this pathology in the republic of North Macedonia from 2011-2020 and simultaneously show the number of cases in every city of Macedonia. The number of cases (by city) is shown in Table 1. All data is provided by the archives of The Institute of Public Health, North Macedonia. Discussion: It is very important to find if there is a correlation between the number of undescended testis cases in North Macedonia to the environment, genetics, level of education, level of health care institutions, etc. Reduced hormonal levels, reduced fertility and increased risk of testicular cancer are the most common side effects of no treatment or late treatment. Conclusion; This condition of the undescended testis is very common, and the possible effects of late treatment or no treatment at all are very risky. So, we have to pay attention to the risks in order to try to provide better treatment at the right point of age.</jats:p> - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Increased risk of brucellosis misdiagnosis in regions that lose their endemicity(Malaysian Society of Parasitology and Tropical Medicine, 2023-03-31); ; Over the last decades, the epidemiology of human brucellosis globally has been subjected to significant changes, with the eradication of many existing endemic hot spots. This paper describes three cases with initial misdiagnosis of brucellosis that were managed during 2011-2017 in Republic of North Macedonia, country that until recently has been declared as endemic region. In spite of the fever, constitutional symptoms, focal disease (spondylitis, pneumonia and orchitis) and previous contact with domestic animals, brucellosis was not initially recognized, and patients were inadequately managed. Brucellosis should be part of differential diagnostic considerations in patients exposed to contacts with animals, with osteoarticular symptoms and signs, constitutional manifestations and different organ involvements in endemic regions where its incidence is diminishing. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Single-center descriptive statistical analysis of glial tumors with reference to glioblastomas(Macedonian Association of Anatomists, 2022-12); ; ; ; Gliomas are the most common primary intracranial brain neoplasms composing almost 80% of all cancerous brain tumours. Glioblastoma is the most common malignant brain tumour in the adult population and accounts in about 15% of all intracranial neoplasms. This observational analytical study gives a better overview of the current state of glial tumours in North Macedonia from 2021 to 2022 with special reference to glioblastomas. Epidemiological and statistical analysis of glial and other brain tumours in a specific time period with special reference to glioblastomas. This research is an observational statistical analysis that takes place on the Institute for Pathology in the Medical Faculty of ‘’Ss. Cyril and Methodius’’ University in Skopje using the digital data base of patients that had undergone surgery in the University Clinic of Neurosurgery and were diagnosed at the Institute of Pathology during the time period 2021-2022. In the period from 2021 and 2022, at the Institute of Pathology were diagnosed 106 (62%) glioblastomas out of which classic glioblastoma histomorphology confined 85 (80.19%) cases; 9 (8.49%) glioblastomas showed oligodendroglial component, 5 (4.72%) cases were gliosarcomas and 4 (3.77%) cases were diagnosed as giant cell glioblastomas. Three (2.83%) cases showed glioblastoma histomorphology with radionecrosis. The results of this descriptive statistical analysis show that glial tumours, especially glioblastomas as most prevalent malignant tumour type deserves greater scientific attention which beside the impact on their diagnostic complexity, will expand the knowledge of this pathology field and strongly reflect on future scientific and diagnostic work. When it comes to global statistics, we can conclude that Republic of North Macedonia follows the global trends regarding the incidence of glioblastoma associated with gender and age. Our results show that glioblastoma is more prevalent in males than females with the ratio male to female being 1.2:1, and this tumour is more prevalent in patients older than 55 years with the average age of diagnosis being 61 years. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Histological and immunohistochemichemical study of malignant lymphomas in Macedonia - Study of 222 cases(Macedonian Association of Pathology, 2013); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Epidemiology of Community-Acquired Sepsis in Adult Patients: A Six Year Observational Study(Macedonian Academy of Sciences and Arts/Sciendo, 2018-07-01); ; ; ; Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to an infection and it is a major cause of morbidity and mortality worldwide. The aim of this study is to describe epidemiology of community-acquired sepsis in the Intensive care unit (ICU) of the Macedonian tertiary care University Clinic for Infectious Diseases. A prospective observational study was conducted over a 6-year period from January, 2011 to December, 2016. All consecutive adults with community-acquired sepsis or septic shock were included in the study. Variables measured were incidence of sepsis, age, gender, comorbidities, season, source of infection, complications, interventions, severity indexes, length of stay, laboratory findings, blood cultures, 28-day and in hospital mortality. Of 1348 admissions, 277 (20.5%) had sepsis and septic shock. The most common chronic condition was heart failure (26.4%), and the most frequent site of infection was the respiratory tract (57.4%). Median Simplified Acute Physiology Score (SAPS II) was 50.0, and median Sequential Organ Failure Assessment (SOFA) score was 8.0. Blood cultures were positive in 22% of the cases. Gram-positive bacteria were isolated in 13% and Gram-negatives in 9.7% of patients with sepsis. The overall 28-day and in hospital mortality was 50.5% and 56.3% respectively. The presence of chronic heart failure, occurrence of ARDS, septic shock and the winter period may influence an unfavorable outcome. Mortality compared to previous years is unchanged but patients that we have been treating these last 6 years have had more severe illnesses. Better adherence to the Surviving Sepsis guidelines will reduce mortality in this group of severely ill patients. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Antibiotics use in relation to asthma in children(Wiley Blackwell, 2018-05); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Harmonized definition of occupational burnout: A systematic review, semantic analysis, and Delphi consensus in 29 countries(Scandinavian Journal of Work, Environment and Health, 2020-12-01)