Faculty of Medicine
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Item type:Publication, ANALYZING OF EMERGENCY APPENDICITIS ADMISSIONS DURING THE COVID-19 LOCK-DOWN IN AN EMERGENCY SURGICAL CORONA CENTER(“Ss. Cyril and Methodius” University, Skopje, R.N. Macedonia, Department of Anaesthesia and Reanimation Faculty of Medicine, 2021-10) ;Stojanoski S ;Spasovski Z ;Krstevski S; ackground: COVID-19 pandemic restrictive measures and the fear of the disease, made a lot of changes in correlation to other actual illnesses. In particular, acute appendicitis as a medical emergency that need fast evaluation and surgery, but still some other medical and non-medical factors influenced its emergency treatment during COVID-19. These factors may also indirectly influence the patients’ outcome. Aim: This study was aimed to evaluate the clinical patterns and outcome of patients who underwent surgery for acute appendicitis during the pandemics. Materials and Methods: In a retrospective manner, data from all patients admitted and surgically treated for acute appendicitis in the General City Hospital “8th of September” (surgi- cal COVID – 19 center in Macedonia) during the period from March 2020 to April 2021, was obtained. Patients according to their PCRs were divided in three groups: COVID-19 negative, COVID-19 positive and post – COVID-19 group. In all patients we analyzed: the type of surgery done, duration of COVID-19 symptoms, duration of surgery, pathohistological findings, need and duration for ICU treatment, hospital stay and mortality. Results: During this period a total of 52 patients underwent appendectomy. Significantly large number of patients underwent open appendectomy. The pathohistological findings showed significantly higher number of perforated appendixes in all groups. Patients from the COVID-19 positive and post-COVID-19 group had longer ICU stay and mortality. Conclusion: Our study analyses showed that during COVID-19 pandemics in our center, patients with appendicitis had higher incidence of perforated appendix, longer length of hospital stay and increased rate of complications. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Acute appendicitis: Covid-19 pandemic did not change presentation and treatment(2022); ;Ulusoy, Cemal ;Dervishov, KristijanOtljanski, AleksandarThis single-tertiary non-Covid center retrospective study analyses the impact on Covid-19 pandemic on the presentation and the treatment in patients operated for acute appendicitis. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Diagnostic Value of The Ischemia Modified Albumin and Pentraxin 3 In Pediatric Appendicitis: A Meta Analysis(2022-07) ;Diego Falchi ;Ayten Ceren Bakir; ;Hani Abu TziamSeçil YükselObjective: In this meta-analysis, we aimed to review the diagnostic value of pentraxin 3 (PTX3) and ischemia-modified albumin (IMA) biomarkers in pediatric appendicitis. Method: Studies focusing on the value of PTX3 and IMA in the diagnosis of appendicitis were searched related to the PubMed database. Only randomized prospective clinical trials were included in this study. Results: After the screening, 6 articles based on the diagnostic value of IMA in appendicitis and 5 articles on the diagnostic value of PTX3 were reviewed. A total of 5 studies were included. The data of the 385 patients were reviewed. Sensitivity of PTX3 was 73-92% and specificity 88-100%, while IMA sensitivity was 89-96.7% and specificity was 26- 99.7% in acute appendicitis. Conclusion: Although the results of the present study indicate that PTX3 and IMA can be shown as biomarkers in the differential diagnosis of acute abdomen, further study is needed to determine the cut-off value
