Faculty of Medicine
Permanent URI for this communityhttps://repository.ukim.mk/handle/20.500.12188/14
Browse
Search Results
- Some of the metrics are blocked by yourconsent settings
Item type:Publication, HYPERTENSIVE DISORDERS IN PREGNANCY-PHYSICIANS’AWARENESS FOR EARLY DETECTION(Македонско лекарско друштво = Macedonian Medical Association, 2019); Abstract Introduction. Hypertensive disorders in pregnancy are a major cause of perinatal morbidity and mortality. Early diagnosis, term delivery, and/or patient’s transfer to a tertiary institution have a huge impact on favorable outcome. Aim. To estimate ob-gyn physician’s awareness for early detection of pregnancy hypertension i.e. for establishing diagnosis before the onset of symptoms. Methods. Study population was consisted of all pregnant women in ≥37 week of gestation admitted to Special Hospital for Obstetrics and Gynecology “Mother Teresa” during the period 15.02-28.02.2018. Тhe study was designed as a retrospective one, and the data were collected by a questionnaire. Additionally, histories of all patients admitted to SHOG “Mother Teresa” between 01.01.2017 and 31.12.2017 under diagnosis of PIH/PE (pregnancy-induced hypertension/pre-eclampsia), were analyzed retrospectively whether the diagnosis was established during the hospital admission or before. Results. Twenty-two percent of pregnant women that underwent regular antenatal check-ups did not have blood pressure measurement taken by their ob-gyn physician at all. Only in 16.7% of cases, the diagnosis was established early, i.e. before the onset of symptoms. Conclusion. The awareness of ob-gyn physicians for early (pre-symptomatic) detection of hypertensive disorders in pregnancy is low. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, CORRELATION BETWEEN SERUM LEVEL OF PLACENTAL GROWTH FACTOR IN FIRST TRIMESTER OF PREGNANCY AND SUBSEQUENT PREECLAMPSIA DEVELOPMENT - А PILOT STUDY(Македонско лекарско друштво = Macedonian Medical Association, 2019); ; Abstract Introduction. Preeclampsia (PE) is one of the leading causes for maternal and perinatal morbidity and mortality. The possibility of PE development prediction is essential for adequate management of this pathology, especially in terms of undertaken measures for disease prevention. Aim. To determine whether there is a correlation between serum levels of Placental Growth Factor (PlGF) in the first trimester of pregnancy with subsequent PE development. Methods. Study population was consisted of 307 pregnant women in the first trimester of pregnancy who had visited Special Hospital for Obstetrics and Gynecology “Mother Teresa” for aneuploidy screening. During this visit, blood was taken for measuring the PlGF level. The study was prospective-observational-cohort. All pregnant women were monitored for PE development until delivery. The group of pregnant women with PE was matched with that without disease by comparing PlGF values. Results. From the initial pool, only 283 participants completed the study. Among them, 7 developed PE. The average PlGF concentration in PE+ group was 32.29 pg/ml (1.06 MoM’s), and in PE-group 45.42 pg/ml (1.58 MoM’s). The difference between the results of the women destined to develop PE in comparison with those who are not, was statistically significant (0.018 and 0.011 for pg/ml and MoM’s respectively). Conclusion. Low serum level of PlGF in the first trimester of pregnancy is correlated with subsequent PE development.