Faculty of Medicine

Permanent URI for this communityhttps://repository.ukim.mk/handle/20.500.12188/14

Browse

Settings

Author: search.filters.author.Zlateska Gjurikj, SofijaHas files: Yes

Search Results

Now showing 1 - 5 of 5
  • Loading...
    Thumbnail Image
    Some of the metrics are blocked by your 
    consent settings
    Item type:Publication,
    ПРОЦЕНКА НА ЕФЕКТИВНОСТА НА ПЛИКАТУРИРАНА КОЛПОСУСПЕНЗИЈА КАЈ ПАЦИЕНТКИ СО СТРЕС УРИНАРНА ИНКОНТИНЕНЦИЈА
    (Македонско лекарско друштво = Macedonian medical association, 2024)
    Zlateska Gjurikj, Sofija
    ;
    ;
    ;
    ;
    Introduction. Urinary incontinence (UI) is a common medical issue that can affect women of all ages. UI is rarely life-threatening, but impacts patients’ mental, physical and social well-being. Ultrasound in urogynecology enables accurate evaluation of both static and dynamic relationships in the lower urinary tract. Methods. This study aimed to demonstrate the use of ultrasound in pre- and postoperative evaluation of patients with SUI. Additionally, it assessed the effectiveness of pleated colposuspension. A total of 40 preoperative SUI patients were included, divided into two subgroups with 20 patients each: the first group was underwent an isolated colposusension, and the second, in addition, underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy. Using transperineal 2D ultrasound, α and β angles were measured at rest and during Valsalva maneuver. Results. The α and β angles were significantly lower in postoperative state compared to the Preoperative one. A t-test confirmed that these increments were statistically significant (p≤0.05). Conclusion. By monitoring α and β angles pre- and postoperatively, clinicians can objectively evaluate the success of surgical interventions for SUI.
  • Loading...
    Thumbnail Image
    Some of the metrics are blocked by your 
    consent settings
    Item type:Publication,
    ПРОЦЕНКА НА УСПЕШНОСТА НА ПЛИКАТУРИРАНА КОЛПОСУСПЕНЗИЈА СО АНАЛИЗА НА Α И Β АГЛИТЕ
    (SHMSHM - AAMD, 2025-07)
    Zlateska Gjurikj, Sofija
    ;
    ;
    Damjanovikj, Aleksandra Zlateska
    ;
    ;
    Уринарна инконтиненција (UI) е честа состојба која може да ги афектира жените во било која возраст и е претставена со широк дијапазон на симптоми. Ретко е животно загрозувачка, но влијае на физичката, менталната и социјалната благостостојба. Ултразвукот во урогинекологијата овозможува евалуација на статички и динамички соодноси на долен уринарен тракт. Материјал и методи: Во оваа студија е прикажана употребата на ултразвукот во пре- и пост- оперативно следење на пациентките со стрес уринарна инонтиненција (SUI). Вкупно 40 жени влегоа во оваа проспективна рандомизирана студија. Беа поделени на две групи од по 20. Со помош на трансперинеален 2D ултразвук, се мереа α и β аглите во мир и во тек на Валсалва маневр. Во првата група беше изведена изолирана колпосуспензија, а во втората група беше направена и тотална абдоминална хистеректомија со билатерална салпингооофоректомија. Резултати:α и β аглите беа сигнификантно помали во тек на постоперативните контроли во споредба со предоперативните вредности на истите. T-тестот го потврди овој инкремент со медицински значајна статистичка сигнификантност(p≤0.05). Заклучок:Со мониторирање на овие два агли пред и постоперативно, може да се добие објективност во клиничката евалуција и проценка на успешноста на хируршкиот третман на SUI.
  • Loading...
    Thumbnail Image
    Some of the metrics are blocked by your 
    consent settings
    Item type:Publication,
    THE EFFICACY OF TRANEXAMIC ACID IN REDUCING PERIOPERATIVE BLOOD LOSS IN TOTAL HIP ARTHROPLASTY
    (Македонско лекарско друштво = Macedonian medical association/De Gruyter, 2025-04)
    ;
    Atanasovski, Igor
    ;
    Komnenovikj, Marina
    ;
    Zlateska Gjurikj, Sofija
    ;
    Zlateska Damjanovikj, Aleksandra
    Total hip arthroplasty (THA) is a common surgical procedure indicated for patients with hip osteoarthritis. A significant concern during THA is perioperative blood loss, which can increase the risk of postoperative anemia and the need for allogeneic blood transfusions. Tranexamic acid (TXA), a synthetic lysine analog, functions by inhibiting plasminogen activation, thereby reducing f ibrinolysis and bleeding. Recent studies have demonstrated its utility in various surgical fields, including orthopedics. A 68-year-old female with a history of chronic osteoarthritis and no significant cardiovascular or thromboembolic events presented for elective primary THA. Preoperative evaluation revealed controlled hypertension and normal coagulation profiles. In view of minimizing intraoperative bleeding and reducing transfusion requirements, the surgical team decided to use TXA as part of the blood management protocol. A single dose of tranexamic acid was administered before the skin incision according to the recommended dosage of 1 gram via slow intravenous infusion (1 ml/minute). The surgery was uneventful, with an estimated blood loss of 1331 mL calculated with the Mercuriali’s formula for blood loss. Postoperative management included routine thromboprophylaxis with enoxaparin 40 mg once daily and early mobilization. Postoperative hemoglobin was 119 g/L, and no transfusion was required. The patient had an uneventful recovery and was discharged on fifth postoperative day. TXA has been shown to significantly reduce blood loss and transfusion rates in THA without increasing thromboembolic risk when used appropriately. Multiple studies support the use of TXA, demonstrating its safety profile even in patients with controlled cardiovascular comorbidities. In this case, TXA administration effectively minimized intraoperative blood loss, maintained postoperative hemoglobin levels, and eliminated the need for transfusion. The use of TXA in THA is a valuable strategy to reduce blood loss and avoid transfusion-related complications. Further research and larger studies will continue to refine optimal dosing strategies and patient selection criteria.
  • Loading...
    Thumbnail Image
    Some of the metrics are blocked by your 
    consent settings
    Item type:Publication,
    COMPLICATIONS AFTER PLEATED COLPOSUSSPENSION
    (Македонско лекарско друштво = Macedonian medical association/De Gruyter, 2025-04)
    Zlateska Gjurikj, Sofija
    ;
    Zlateska Damjanovikj, Aleksandra
    ;
    ;
    Ilkoski, Ana
    ;
    The case is about a 60-year-old woman with abdominal swelling, lower abdominal cramps, and occasional urine leakage triggered by coughing, sneezing, or laughing. She had no nocturia or urgency symptoms but reported significant social discomfort. Her history included two vaginal deliveries. A pelvic exam revealed mild urethral hypermobility during Valsalva, no significant pelvic organ prolapse, and a highly positive Marshall test for stress urinary incontinence (SUI). Additionally, a firm, mobile mass was palpated in the right abdomen. Ultrasound identified a 13 cm cystic formation in the right ovary with thick edges and no solid components. To assess malignancy risk, we applied our original ROMI index, evaluating serum CA-125 levels, menopausal status, personal and familial history, and ultrasound features. The patient’s ROMI score was 6, indicating low malignancy risk. Laparotomy revealed a large retroperitoneal mass adhering to the right ureter, necessitating J-J stent placement. A successful tumor excision was performed, followed by an abdominal hysterectomy and our modified Pleated Colposuspension after Antovska for SUI correction.
  • Loading...
    Thumbnail Image
    Some of the metrics are blocked by your 
    consent settings
    Item type:Publication,
    EVALUATION OF TOTAL BLOOD LOSS AFTER ADMINISTRATION OF TRANEXAIMC ACID IN TOTAL HIP ARTHROPLASTY
    (MIT University Skopje, 2025-03)
    ;
    ;
    ;
    ;
    Total arthroplasty is one of the most frequent procedures in orthopedic surgery, proven to be an effective treatment that significantly improves patients' quality of life. However, it is associated with considerable perioperative blood loss which can lead to suboptimal outcomes and systemic complications. The aim of this study is to assess the total blood loss after the application of tranexamic acid in patients undergoing total hip arthroplasty surgery. A total of 64 patients were included, divided into two groups: a test group where tranexamic acid was administered intravenously and a control group where tranexamic acid was not used. The values for total blood loss and erythrocyte volume loss were statistically significantly lower in the test group. Blood loss in the control group was higher by an average of 482.19 ml. Erythrocyte loss in the control group was higher by an average of 256.28 ml. The use of tranexamic acid as a standard protocol in total hip arthroplasty is a safe and effective method to reduce total blood loss. Ultimately, this results in a reduced need for blood transfusion, a decrease in potential risks and complications associated with it, and the achievement of pharmacoeconomic benefits.