Faculty of Medicine
Permanent URI for this communityhttps://repository.ukim.mk/handle/20.500.12188/14
Browse
7 results
Search Results
- Some of the metrics are blocked by yourconsent settings
Item type:Publication, Phyllodes tumor- Case report(Macedonian Association of Radiologists, 2023-11); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, CT Findings in Progressive Xanthogranulomatous Pyelonephritis(Department of Anaesthesia and Reanimation, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R.N. Macedonia, 2023) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Unveiling the neuropathology tumour landscape: 10-year statistical analysis with global comparison – Single centre experience(Macedonian Academy of Sciences and Arts, 2023-12); ; ; ; Introduction: Central nervous system (CNS) tumours represent a significant public health issue worldwide, and their incidence and distribution vary across different populations. Although studies on CNS tumours have been conducted in various countries, there is a lack of information regarding their patterns in Macedonia. Therefore, this study is aimed at investigating the distribution, histopathological types and subtypes and demographic features of CNS tumours in our country. Materials and Methods: A cross sectional study was conducted using the electronic database of the Institute of Pathology – Medical Faculty, University “Ss. Cyril and Methodius” in Skopje which contains data from 3286 received and analysed surgical specimens, mainly from the University Clinic of Neurosurgery in Skopje, and a smaller number of surgical specimens from the University Surgical Centre “St. Naum Ohridski” in Skopje between 2012 and 2022. The collected and analysed data includes patient age, sex and histopathological types and subtypes of the tumours. Results: The majority of CNS tumours were diagnosed in adults aged between 50-70, with a male to female ratio of 1.5:1. The most common location of the tumours was the cerebrum, followed by the pituitary gland and cerebellum. The most frequent histological groups were gliomas, with glioblastoma as the most common diagnosis, followed by meningiomas. Conclusion: Following a detailed and thorough review of the CNS tumours in our study, we can conclude that the R. of Macedonia follows global statistics and trends regarding brain tumours. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, CONTEMPORARY ASPECTS IN THE PATHOGENESIS OF BRAIN EDEMA IN PATIENTS WITH HEMORRHAGIC CEREBROVASCULAR INSULT(2020-07); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, The role of TNF-α-based models in prognostication of the outcomes after ICH: a pilot study(2019-10); ; ; Abstract Introduction: Recently, we have developed TNF-α-based models for prognostication of the 3-month neurological outcome in patients after Intracerebral hemorrhage, ICH (Rendevski et al., 2018). In this pilot study, we aimed to test their utility in the clinical practice for the purposes of identification of the patients who will most likely end up with a poor outcome, as well as to test their utility for clinical decision making between conservative and surgical intervention. Methods: 20 patients with ICH were included initially in this pilot longitudinal study. Their peripheral blood TNF-α levels were screened, and the risk for poor outcome was assessed by using our previously determined cutoff value of > 110.35 pg/mL. The neurological outcome was determined 3 months after the initial hemorrhagic cerebrovascular insult. Another series of 20 threatened patients with TNF-α levels higher than 200 pg/mL were tested for the possibility of lowering the risk of the poor outcome by implementing early craniotomy with hematoma evacuation. Results: The value of > 110.35 pg/mL had fairly identified the patients who later fell into the group with poor outcome, 3 months after ICH (8 out of 9 identified patients with risk for poor outcome have resulted in a poor outcome). In the second series of 20 threatened patients with TNF-α levels higher than 200 pg/mL, early craniotomy and evacuation of the hematoma were shown beneficial; 7 out of 20 patients resulted in a good outcome. Conclusions: TNF-α screening at admission was shown as a useful method for identifying the ICH patients with the highest risk for ending with poor neurological outcome; early craniotomy with hematoma evacuation in the threatened group of patients with the highest TNF-α levels has also shown benefit in lowering the risk for poor outcome and improving patient's neurological state 3 months after ICH. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Inflammatory and oxidative stress markers in intracerebral hemorrhage: preliminary new insights from machine learning and virtual models of infection(2022-12); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, The impact of glutamate in the development of brain edema in patients with ICH(2016-09); ;