Faculty of Medicine

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    Comparing results between the patients with choroidal neovascularization(CNV) in age related macula r degeneration (AMD) who had no treatment to those who
    (SOE, 2001-06)
    Josifova Т.
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    Ivanovska M.
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    Blazevska K.
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    Ristova J.
    The aim of this stud is to show whether the patients with CNV in cases of AMD who underwent a LPC have a beneficial effect compared to the patients who have a natural history of the disease. Materials and Methods: In the period of 1997-1998 a clinical and fluorescein angiographical investigation was made in order to determinate the CNV in cases with AMD. A subgroup of 64 patients with extra foveolar and juxta foveolar AMD, who had initial lesion that ranged between 1 and 3 MPS disc areas was included in the study. The visual acuity(VA) ranged between finger counting and 20/100. 29 patients underwent Argon Laser Photocoagulation versus 35 who had no treatment. The follow-up period was 24 months. with monitoring of the patients every three months. Results: Persistent CNV was seen in 11/29 (37.9%) patients, and recurrent CNV occurred in 14/29 (48,2%) in the treated eyes within the follow-up period. The VA in the treated group showed that the baseline VA was maintained in 8/29 (27.5%), versus the non-treated group with 17/35 (20.5%) patients. Improvement of the VA in the treated group was seen in 4/29 (13.7%), compared to non-treated group 2/35 (5.7%). From the whole number of treated patients who had visual loss, a severe visual loss was seen in 7/17 (41.1%), while the number of the patients with severe visual loss in the non-treated group was 8/16 (50%). Conclusion: Having no big differences between the treated and non-treated group with CNV in AMD, LPC is an alternative but not a satisfactory method in the treatment of these patients.
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    Results of laser therapy in cases with retinal vein occlusions
    (Bulgarian Society of Ophthalmology, 2000-09)
    Josifova T
    ;
    Ivanovska M.
    ;
    Blazevska K
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    ;
    Nikolovska V.
    Purpose: of this study is to show the effect of laser therapy (LT) of the neovascularization and vitreal hemorrhage in cases with retinal vein occlusions (RVO). On the other hand is shown the effect of the same therapy on the macular edema and the visual acuity (VA). Method: The study includes 30 patients with central retinal vein occlusion (CRVO) and 51 with branch retinal vein occlusion (BRVO). 12/30 patients with CRVO had an ischemic form with neovascularization while the rest 18/30 had an ischemic form without neovascularization. 19/51 patients with BRVO had an ischemic form followed by neovascularization, 32/51 had nonischemic form with macular edema. Scatter photocoagulation was done in the ischemic forms while in the nonischemic forms with macular edema we have performed a grid photocoagulation with a follow up period of 10-24months. The LT was done with Argon Green Laser Photocoagulation - Coherent Novus 2000. Results: Regression of the neovascularization after the scatter photocoagulation was seen in 25/31 patients. Vitreal hemorrhage showed up in 3/29 patients, but only in the group of the patients with CRVO. Two of them had a spontaneous resorption while in the third one a vitrectomy was done. 20/32 patients ameliorated VA by 2 or more lines, 8/32 had the same VA while 4/32 had a decrease in VA after the grid photocoagulation. Conclusions: The scatter photocoagulation enables high percentage regression of the neovascularization and it's a prevention against serious complications in RVO. On the other hand, performing the grid photocoagulation improves the VA, although it isn't significant for a long-term follow up period.
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    Item type:Publication,
    Wagner-Stickler disease A case report
    (1998-06)
    Sofronieva - Ivanovska G
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    Ivanovska M.
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    Wagner-Stickler disease. A case report The authors report a case of Wagner-Stickler disease an a 18-years old boy. Examination of the both eyes revealed optically empty vitreous cavity, resulting from extensive vitreous liquefaction and retinal veils oriented circumferentially. Other ocular findings include high myopic, lattice degeneration and optic atrophy. Retinal detachment developed in his left eye. Clinical appearance and preventive treatment are discussed.
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    The use of topical dorzolamide in uveitis patients with CME
    (Bulgarian society of Ophthalmology, 2000-09)
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    Boshnakovska S.
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    Ivanovska M.
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    Josifova T.
    Purpose: THE AIM OF THIS PILOT STUDY WAS TO ASSESS THE EFFECTIVENESS OF DORZOLAMIDE FOR THE MANEGEMEND OF INFALMATORUM CHRONIC CYSTOID MACULAR EDEMA. Method: TEN PATIENTS (16 EYES )WITH UVEITIS-INDUCED CME RECEIVED 2% DORZOLAMIDE DROPS T.I.D. IN ADDITION TO THE THEIR NORMAL MEDICATION.AT EACH VISIT,BEST CORECTIED VISUAL ACUITY WAS MEASURED AND A FLUORESCEIN ANGIOGRAM WAS OBTAINED. Results: NO PATIENT SHOWED WORSENING OF THE CLINICAL FINDINGS.VISUAL ACUITY WAS IMPROVED BY 2 LINES OR BETTER IN 50%. VISUAL ACUITY COULD NOT BE IMPROVED IN THE REST OF THEM.IMPROVEMENT IN THE AMOUNT OF FLURESCEIN LEAKAGE COULD BE OBSERVED IN 12 EYES (7 PATIENTS). Conclusions: TOPICAL DORZOLAMIDE MAY INFLUENCE THE OUTCOME OF CME IN UTEITIS PATIENTS IN ADDITION TO ITS OCULAR HIPOTENSIVE EFFECTS.
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    Item type:Publication,
    PTERYGIUM-a case report
    (2006)
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    Ivanovska M.
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    Antova M
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    Dzajkovska E
    A sporadic case of bilateral nasal and temporal pterygium on both eyes is present in this abstract. After four operations on all pterigia with limbal conjunctival autotransplantation from superior and inferior part of the bulbar conjunctiva there was no recurrence of the pterygium. The postoperative vision was improved. Pathohistological investigation of the pterygium samples confirmed the diagnosis.