The use of topical dorzolamide in uveitis patients with CME

Date Issued
2000-09
Author(s)
Boshnakovska S.
Ivanovska M.
Josifova T.
Abstract
Purpose: THE AIM OF THIS PILOT STUDY WAS TO ASSESS THE
EFFECTIVENESS OF DORZOLAMIDE FOR THE MANEGEMEND OF
INFALMATORUM CHRONIC CYSTOID MACULAR EDEMA.
Method:
TEN PATIENTS (16 EYES )WITH UVEITIS-INDUCED CME RECEIVED
2% DORZOLAMIDE DROPS T.I.D. IN ADDITION TO THE THEIR NORMAL
MEDICATION.AT EACH VISIT,BEST CORECTIED VISUAL ACUITY WAS
MEASURED AND A FLUORESCEIN ANGIOGRAM WAS OBTAINED.
Results:
NO PATIENT SHOWED WORSENING OF THE CLINICAL
FINDINGS.VISUAL ACUITY WAS IMPROVED BY 2 LINES OR BETTER IN
50%. VISUAL ACUITY COULD NOT BE IMPROVED IN THE REST OF
THEM.IMPROVEMENT IN THE AMOUNT OF FLURESCEIN LEAKAGE
COULD BE OBSERVED IN 12 EYES (7 PATIENTS).
Conclusions:
TOPICAL DORZOLAMIDE MAY INFLUENCE THE OUTCOME OF
CME IN UTEITIS PATIENTS IN ADDITION TO ITS OCULAR HIPOTENSIVE
EFFECTS.
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