Faculty of Medicine

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    ANALYSIS OF THE OCCURRENCE OF POSTOPERATIVE PULMONARY COMPLICATIONS AFTER LUNG SURGERY
    (MIT University Skopje, 2023)
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    Cholancevski, Risto
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    Andov, Mishel
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    Gacovski, Aleksandar
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    Nedxati, J
    Introduction: Postoperative Pulmonary Complications (PPCs) reported after lung surgeries are correlated with increased morbidity and mortality. Literature does not emphasize factors that lead to PPCs. Aim of this study was to evaluate clinical data in patients who developed PPCs after lung surgery. Material and method: This study included data analyses from patients with malignancy aged <79, ASA I-III scheduled for lung surgery was during 3-year period. Obtained patient data was divided in two groups, Group PPCs (n=30)- patient with PPC and control group (n=30) that included patients without PPC. Demographic, clinical preoperative and preoperative data was analyzed, compared between both groups. Results: Patients in Group PPC were significantly older than the control group. Patients in the analyzed group had more comorbidities, lower levels of FEV1%, FVC% even though not statistically significant. The time of one lung ventilation was 132+ 54.3 vs 109.9+42 in respect to the groups and was statistically significantly different between the groups. The most common PPCs found was pneumonia. Conclusion: According to our study patients who are at risk to develop PPCs are patients who are older and who had longer time of one lung ventilation during surgery The most common PPC after lung surgery is pneumonia.
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    MARIJUANA-INDUCED ACUTE CORONARY SYNDROME IN A YOUNG PATIENT
    (Department of Anaesthesia and Reanimation, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R.N. Macedonia, 2023)
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    Jovanoski, Mario
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    Andov, Mishel
    Introduction: Acute coronary syndrome (ACS) is generally a natural consequence of the progression of coronary atherosclerosis. But in minority of cases, it might be developed due to non-atherosclerotic reasons including recreational marijuana use. Possible pathophysiological mechanisms include inflammation, procoagulant state and vasoconstriction (vasospasm) of the coronary arteries. Marijuana adverse effects on cardiovascular system are various and well documented. Case report: We present a 29-years old male who was referred to our Clinic due to chest pain and morphologic ECG changes. The patient has been previously hospitalized in local hospital due to hematochezia. Because of the chest pain, ECG was performed, and blood sample was taken there to determine the troponin level (hs-Tn I). ST-segment elevation and high level of hsTn I were indication for urgent transfer of the patient to our clinic. After admission, the patient underwent coronary angiography and PCI. Thoroughly taken history revealed that the patient was occasionally smoking marijuana in recreational purposes. He was a cigarette smoker, but he had no additional known risk factors for CAD. Conclusion: Recreational marijuana use may be a trigger factor for an acute coronary syndrome. We should always think and suspect marijuana and other recreational drugs as a potential risk factor for adverse cardiovascular events in young patients.