The Level of Cholesterol in COPD Patients with Severe and Very Severe Stage of the Disease
Journal
Open Access Macedonian Journal of Medical Sciences
Date Issued
2016-06-15
Author(s)
Sasha Anastasova
Angela Debresliovska
Sead Zejnel
Dragana Stojkovikj
Abstract
BACKGROUND:
High blood cholesterol is part of metabolic syndrome and can be caused by
medical conditions or bad dietary habits.
AIM:
The aim of the study was to investigate the prevalence of hypercholesterolemia in privies
diagnosed patients with the severe and very severe stage of COPD, which аre stable.
MATERIAL AND METHODS:
We investigated 100 subjects, all of them smokers, with smoking status >10 years, stratified
into two groups: with severe and very severe stage of the disease. It was clinical, randomized, cross-sectional
study. Besides demographic parameters and functional
parameters, body mass index, cholesterol, LDL, and HDL were investigated.
RESULTS: In the group of patients with very severe COPD were recorded significantly higher
average values of cholesterol (6.16 ± 1.5 vs.5.61 ± 1.1,p = 0.039). As independent significant
factors influencing cholesterol in the group with a very severe COPD were confirmed the age of the
patients (p = 0.005), LDL (p = 0.004) and HDL (p = 0.002). In the group with severe COPD, only LDL was confirmed as an independent significant factor that has an impact on cholesterol (p <0.0001).
CONCLUSION: The results of our survey demonstrated a high level of blood cholesterol and LDL,
and low level of blood HDL in both investigated group’s patients with COPD
High blood cholesterol is part of metabolic syndrome and can be caused by
medical conditions or bad dietary habits.
AIM:
The aim of the study was to investigate the prevalence of hypercholesterolemia in privies
diagnosed patients with the severe and very severe stage of COPD, which аre stable.
MATERIAL AND METHODS:
We investigated 100 subjects, all of them smokers, with smoking status >10 years, stratified
into two groups: with severe and very severe stage of the disease. It was clinical, randomized, cross-sectional
study. Besides demographic parameters and functional
parameters, body mass index, cholesterol, LDL, and HDL were investigated.
RESULTS: In the group of patients with very severe COPD were recorded significantly higher
average values of cholesterol (6.16 ± 1.5 vs.5.61 ± 1.1,p = 0.039). As independent significant
factors influencing cholesterol in the group with a very severe COPD were confirmed the age of the
patients (p = 0.005), LDL (p = 0.004) and HDL (p = 0.002). In the group with severe COPD, only LDL was confirmed as an independent significant factor that has an impact on cholesterol (p <0.0001).
CONCLUSION: The results of our survey demonstrated a high level of blood cholesterol and LDL,
and low level of blood HDL in both investigated group’s patients with COPD