Korelacioni mes rashësisë së endometriumit dhe qasjes patohistolog jike te pacientet në postemnopauzë
Journal
Medicus
Date Issued
2017-10
Author(s)
Abstract
Aim of the study was to trial to investigate the validity of the detected ultrasonic thickness of the endometrium
in the prediction of endometrial cancer in postmenopausal patients with and without uterine bleeding, confirmed
by histopathological analysis of material obtained by exploratory curettage of the endometrium. Material and Methods: This study included 120 patients recruited in post-menopausal age of the University Clinic
of Gynecology and Obstetrics - Skopje, who were divided into two groups. Test group included 80 patients with
postmenopausal detected ultrasonic endometrial thickness greater than or equal to 5mm. They were divided into
two subgroups - subgroup A: Patients with uterine bleeding (40 patients) and subgroup B: patients without uterine
bleeding (40 patients), which were divided based on ultrasound endometrial thickness of endometrium of 5-8mm;
from 8-11mm; more than 11mm. The control group included 40 postmenopausal patients hospitalised because
urogynecological pathology with previous ultrasound detected endometrial thickness of less than 5mm and
orderly histopathological findings derived from material in exploratory curettage of endometrium. In each patient
detailed history was taken and curettage exploratory fractionated and material was send to histopathological
analysis.
Results. The thickness of the endometrium is endometrial significant predictor of malignancy (p <0,05). With
each millimeter increase in endometrium significantly increases the likelihood of endometrial malignancy of 1,178
[p = 0,002, 95% CI = 1,065-1,304] times.
Conclusion: In postmenopausal patients likelihood of endometrial cancer significantly increases by 1,178 times.
in the prediction of endometrial cancer in postmenopausal patients with and without uterine bleeding, confirmed
by histopathological analysis of material obtained by exploratory curettage of the endometrium. Material and Methods: This study included 120 patients recruited in post-menopausal age of the University Clinic
of Gynecology and Obstetrics - Skopje, who were divided into two groups. Test group included 80 patients with
postmenopausal detected ultrasonic endometrial thickness greater than or equal to 5mm. They were divided into
two subgroups - subgroup A: Patients with uterine bleeding (40 patients) and subgroup B: patients without uterine
bleeding (40 patients), which were divided based on ultrasound endometrial thickness of endometrium of 5-8mm;
from 8-11mm; more than 11mm. The control group included 40 postmenopausal patients hospitalised because
urogynecological pathology with previous ultrasound detected endometrial thickness of less than 5mm and
orderly histopathological findings derived from material in exploratory curettage of endometrium. In each patient
detailed history was taken and curettage exploratory fractionated and material was send to histopathological
analysis.
Results. The thickness of the endometrium is endometrial significant predictor of malignancy (p <0,05). With
each millimeter increase in endometrium significantly increases the likelihood of endometrial malignancy of 1,178
[p = 0,002, 95% CI = 1,065-1,304] times.
Conclusion: In postmenopausal patients likelihood of endometrial cancer significantly increases by 1,178 times.
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