Effect of Intraoperative High Positive End-Expiratory Pressure (PEEP) With Recruitment Maneuvers vs Low PEEP on Postoperative Pulmonary Complications in Obese Patients: A Randomized Clinical Trial

Bluth, Thomas; Serpa Neto, Ary; Schultz, Marcus J; Pelosi, Paolo; Gama de Abreu, Marcelo; Bluth, T; Bobek, I; Canet, J C; Cinnella, G; de Baerdemaeker, L; Gama de Abreu, M; Gregoretti, C; Hedenstierna, G; Hemmes, S N T; Hiesmayr, M; Hollmann, M W; Jaber, S; Laffey, J; Licker, M J; Markstaller, K

doi:10.1001/jama.2019.7505

Effect of Intraoperative High Positive End-Expiratory Pressure (PEEP) With Recruitment Maneuvers vs Low PEEP on Postoperative Pulmonary Complications in Obese Patients: A Randomized Clinical Trial

Journal

JAMA

Date Issued

2019

Author(s)

Bluth, Thomas

Serpa Neto, Ary

Schultz, Marcus J

Pelosi, Paolo

Gama de Abreu, Marcelo

Bluth, T

Bobek, I

Canet, J C

Cinnella, G

de Baerdemaeker, L

Gama de Abreu, M

Gregoretti, C

Hedenstierna, G

Hemmes, S N T

Hiesmayr, M

Hollmann, M W

Jaber, S

Laffey, J

Licker, M J

Markstaller, K

Matot, I

Mills, G H

Mulier, J P

Pelosi, P

Putensen, C

Rossaint, R

Schmitt, J

Schultz, M J

Senturk, M

Serpa Neto, A

Severgnini, P

Sprung, J

Vidal Melo, M F

Wrigge, H

Collaborators+

DOI

10.1001/jama.2019.7505

Abstract

An intraoperative higher level of positive end-expiratory positive pressure (PEEP) with alveolar recruitment maneuvers improves respiratory function in obese patients undergoing surgery, but the effect on clinical outcomes is uncertain.