EVALUATION OF THE CHANGES OF ACID-BASE STATUS AND THE SERUM SODIUM CONCENTRATION IN TRANSURETRAL RESECTION OF PROSTATE
Journal
Macedonian Journal of Anaesthesia
Date Issued
2017-04
Author(s)
Petrova Chemeski, N
Abstract
Objective: Transurethral resection of the prostate (TURP) is endoscopic urological
intervention used in the treatment of BPH. A possible complication in TURP procedure is systemic
absorption of the hypotonic irrigation fluid known as TURP syndrome. Here we evaluate changes
in the level of electrolyte and acid-base status during TURP, correlation of hyponatremia and
acidosis in the appearance of TURP syndrome and the impact of the duration of the procedure
on the level of hyponatremia and acidosis.
Methods and results: 20 male patients were divided into 2 groups according to the
length of intervention: Group 1 (n = 9) less than 60 minutes and Group 2 (n = 11) more
than 60 minutes. All TURP procedures were performed under general anesthesia and sterile
water was used as irrigant. The level of Na +, K + and Cl-, pH, bicarbonate, lactate, base
excess and Hb were determined through arterial blood pre-, intra- and postoperatively.
Conclusions: Postoperative values of the second group indicated significant hyponatremia
and hypochloraemia compared to the preoperative values and acidosis with fall in pH of
7.41 to 7.37 compared to the first group of patients. Changes in both groups of patients are
directly proportional to the volume of irrigation fluid, the duration of the procedure and the
weight of the recessed prostatic tissue. In all of the cases there were changes in the examined
variables, indicating a need for monitoring of electrolytes and acid-base parameters periand
postoperatively as an opportunity for early detection and treatment of TURP syndrome.
intervention used in the treatment of BPH. A possible complication in TURP procedure is systemic
absorption of the hypotonic irrigation fluid known as TURP syndrome. Here we evaluate changes
in the level of electrolyte and acid-base status during TURP, correlation of hyponatremia and
acidosis in the appearance of TURP syndrome and the impact of the duration of the procedure
on the level of hyponatremia and acidosis.
Methods and results: 20 male patients were divided into 2 groups according to the
length of intervention: Group 1 (n = 9) less than 60 minutes and Group 2 (n = 11) more
than 60 minutes. All TURP procedures were performed under general anesthesia and sterile
water was used as irrigant. The level of Na +, K + and Cl-, pH, bicarbonate, lactate, base
excess and Hb were determined through arterial blood pre-, intra- and postoperatively.
Conclusions: Postoperative values of the second group indicated significant hyponatremia
and hypochloraemia compared to the preoperative values and acidosis with fall in pH of
7.41 to 7.37 compared to the first group of patients. Changes in both groups of patients are
directly proportional to the volume of irrigation fluid, the duration of the procedure and the
weight of the recessed prostatic tissue. In all of the cases there were changes in the examined
variables, indicating a need for monitoring of electrolytes and acid-base parameters periand
postoperatively as an opportunity for early detection and treatment of TURP syndrome.
File(s)![Thumbnail Image]()
Loading...
Name
MJA 1 nomer.pdf
Size
1.55 MB
Format
Adobe PDF
Checksum
(MD5):72503e03786ef6aebcc682c57e6c8884