Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12188/8820
DC Field | Value | Language |
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dc.contributor.author | Stojanoski, Sinisa | en_US |
dc.contributor.author | Ristevska, Nevena | en_US |
dc.contributor.author | Pop Gjorcheva, Daniela | en_US |
dc.contributor.author | Antevski, Borce | en_US |
dc.contributor.author | Petrushevska, Gordana | en_US |
dc.date.accessioned | 2020-08-24T11:12:48Z | - |
dc.date.available | 2020-08-24T11:12:48Z | - |
dc.date.issued | 2015-05-01 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.12188/8820 | - |
dc.description.abstract | <jats:title>Abstract</jats:title> <jats:p> Introduction: Breast cancer accouns for 22.9% of all cancers in women and 13.7% of cancer deaths. Positive axillary lymphnodes (ALN) predict the development of distant metastases. The status of the sentinel lymphnode (SLN) is crutial for the treatment selection. </jats:p> <jats:p>Aim: To determine the benefits of SLN detection in patients with breast cancer. Material and methodology: 38 female patients (pts), age 44 ± 12 years, with T1-2 N0 M0 breast cancer, without enlarged ALN on ultrasound (US), were included. SLN detection was performed using gamma camera and gamma detection probe after periareolar subcutaneous and/or peritumoral injection of (99m-Technetium-SENTISCINT). Blue dye was administered 20 min before the operation. SLN was extirpated and ex tempore histopathology was performed. </jats:p> <jats:p>Results: Ex tempore SLN evaluation was negative and the lymphatic pathways preserved in 28/38 (74%) pts. In 10/38 (26%) pts SLN was positive, followed by radical surgery. In 3/28 ex tempore negative patients, histopathological analysis showed metastatic involvement (false negative). In 3/10 ex tempore positive patients micro metastases 0,2-2 mm were detected. 12 pts had 2 SLN, 8/12 (66%) had negative and 4/12 (34%) had positive SLN. 3 pts had a rare double drainage to axilla and a. mammaria int. </jats:p> <jats:p>Conclusion: Our results confirm that SLN detection technique is non-invasive, safe and reliable and should be incorporated into the guidelines for breast cancer pts (T1-2 N0 M0). The most reliable option for colloid application is the combined technique of periareolar and peritumoral injection. Patients with drainage to a. mammaria interna should be selected for adjuvant protocols.</jats:p> | en_US |
dc.publisher | Macedonian Academy of Sciences and Arts / Walter de Gruyter GmbH | en_US |
dc.relation.ispartof | Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki) | en_US |
dc.title | Sentinel Lymph Node Detection in Breast Cancer – First Experience | en_US |
dc.title.alternative | Детекција на сентинелни лимфни Јазли кај карцином на дојка – први искуства | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1515/prilozi-2015-0039 | - |
dc.identifier.url | http://content.sciendo.com/view/journals/prilozi/36/1/article-p145.xml | - |
dc.identifier.url | https://www.degruyter.com/view/j/prilozi.2015.36.issue-1/prilozi-2015-0039/prilozi-2015-0039.pdf | - |
dc.identifier.volume | 36 | - |
dc.identifier.issue | 1 | - |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
crisitem.author.dept | Faculty of Medicine | - |
crisitem.author.dept | Faculty of Medicine | - |
crisitem.author.dept | Faculty of Medicine | - |
crisitem.author.dept | Faculty of Medicine | - |
Appears in Collections: | Faculty of Medicine: Journal Articles |
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