Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12188/8690
Title: Evaluation of the role of left atrial strain using two-dimensional speckle tracking echocardiography in patients with diabetes mellitus and heart failure with preserved left ventricular ejection fraction
Authors: Ljubica Georgievska-Ismail 
Planinka Zafirovska
Zarko Hristovski
Keywords: left atrial deformation
speckle tracking echocardiography
diabetes mellitus
heart failure with preserve left ventricular ejection fraction
Issue Date: 12-Jul-2016
Publisher: SAGE Publications
Journal: Diabetes and Vascular Disease Research
Abstract: Abstract Objective: To evaluate additional role of left atrial two-dimensional speckle tracking echocardiography in patients with diabetes mellitus type 2, 218 patients with heart failure with preserved left ventricular ejection fraction divided according to the presence of diabetes mellitus (108 with and 110 without) were enrolled in the study. Methods: Traditional parameters using two-dimensional echocardiography and Doppler imaging were measured as expressions of left ventricular diastolic function as well as peak atrial longitudinal strain and peak atrial contraction strain were measured using two-dimensional speckle tracking echocardiography. Results: Global average peak atrial longitudinal strain and peak atrial contraction strain were significantly lower in patients with diabetes mellitus (p = 0.002 and p = 0.001, respectively) and its reduced values were significantly associated with higher prevalence of diabetes mellitus (p=0.002 and p=0.001, respectively), its greater severity (p=0.002 and p=0.016, respectively) and longer duration only for global average peak atrial longitudinal strain (p=0.030). Multiple linear regression analysis demonstrated that the presence of diabetes mellitus appeared as independent predictor of reduced global peak atrial longitudinal strain [B=−2.173; 95% confidence interval: −3.870 to (−0.477); p=0.012] as well of reduced global peak atrial contraction strain [B=−1.30; 95% confidence interval: −2.234 to (−0.366); p=0.007]. Conclusion: Two-dimensional speckle tracking echocardiography appeared as a useful additional tool for detection of left atrial dysfunction in patients with heart failure who have preserved left ventricular ejection fraction and diabetes mellitus who are especially prone to develop cardiovascular complications.
URI: http://hdl.handle.net/20.500.12188/8690
DOI: 10.1177/1479164116655558
Appears in Collections:Faculty of Medicine: Journal Articles

Files in This Item:
File Description SizeFormat 
Georgievska-Diab and Vascu Dis Res-2016.pdf797.87 kBAdobe PDFThumbnail
View/Open
Show full item record

Page view(s)

49
checked on Mar 28, 2024

Download(s)

14
checked on Mar 28, 2024

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.