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Title: Tertiary Lymphoid Structures in Colorectal Cancers and Their Prognostic Value
Authors: Trajkovski, Gjorgji
Ognjenovic, Ljubomir
Karadzov, Zoran
Jota, GJorgji 
Hadzi-Manchev, Dragan
Ognen Kostovski 
Volcevski, Goce
Trajkovska, Vanja
Nikolova, Dafina 
Spasevska, Liljana 
Janevska, V
Janevski, Vlado 
Issue Date: 25-Oct-2018
Publisher: ID Design 2012/DOOEL Skopje
Journal: Open Access Macedonian Journal of Medical Sciences 
Abstract: Tumor-infiltrating lymphocytes (TIL) in tumour stroma are considered to be involved in the elimination of malignant cells and prevention of metastasis formation. TIL consist of T lymphocytes including cytotoxic lymphocytes that are a constituent part of the effector mechanism of anti-tumour immunity and B lymphocytes that can form tertiary lymphoid structures (TLS). TLS has been described in several solid tumours and colorectal carcinoma (CRC), and the influence on the local and systemic anti-cancer response.
ISSN: 1857-9655
DOI: 10.3889/oamjms.2018.341
Appears in Collections:Faculty of Medicine: Journal Articles

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