Smichkoska, Snezhana

Preferred name

Official Name

Smichkoska, Snezhana

Translated Name

Смичкоска, Снежана

Alternative Name

S, Smichkoska

S, Smickova

S, Smichkova

S, Smickoska

Smickova, Snezana

Smickoska, Snezana

Smichkoska, S

Smickova, S

Smichkova, S

Smickoska, S.

Main Affiliation

snezana.smickoska@medf.ukim.edu.mk

smicko@t.mk

Now showing 1 - 10 of 59

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CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers
(Springer Science and Business Media LLC, 2021-02)
Johnson, Nichola
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Maguire, Sarah
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Morra, Anna
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Kapoor, Pooja Middha
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Tomczyk, Katarzyna
Epidemiological studies provide strong evidence for a role of endogenous sex hormones in the aetiology of breast cancer. The aim of this analysis was to identify genetic variants that are associated with urinary sex-hormone levels and breast cancer risk.
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Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial
(Elsevier BV, 2017-12)
Martin, Miguel
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Holmes, Frankie A
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Ejlertsen, Bent
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Delaloge, Suzette
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Moy, Beverly
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Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment
(Springer Science and Business Media LLC, 2021-08-18)
Morra, Anna
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Escala-Garcia, Maria
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Beesley, Jonathan
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Keeman, Renske
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Canisius, Sander
Given the high heterogeneity among breast tumors, associations between common germline genetic variants and survival that may exist within specific subgroups could go undetected in an unstratified set of breast cancer patients.
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Availability of technology for managing cancer patients in the Southeast European (SEE) region
(Elsevier BV, 2022-03)
Dosanjh, Manjit
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Georgieva, Petya
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Balin Kovacevic, Marijana
Background: The Southeast European (SEE) region of 10 countries and about 43 million people differs from Western Europe in that most SEE countries lack active cancer registries and have fewer diagnostic imaging devices and radiotherapy (RT) units. The main objective of this research is to initiate a common platform for gathering SEE regional cancer data from the ground up to help these countries develop common cancer management strategies. Methods: To obtain detailed on-the-ground information, we developed separate questionnaires for two SEE groups: a) ONCO - oncologists regarding cancer treatment modalities and the availability of diagnostic imaging and radiotherapy equipment; and b) REG - national radiation protection and safety regulatory bodies regarding diagnostic imaging and radiotherapy equipment in SEE facilities. Results: Based on responses from 13/17 ONCO participants (at least one from each country) and from 9/10 REG participants (all countries but Albania), cancer incidence rates are higher in those SEE countries that have greater access to diagnostic imaging equipment while cancer mortality-to-incidence (MIR) ratios are higher in countries that lack radiotherapy equipment. Conclusion: By combining unique SEE region information with data available from major global databases, we demonstrated that the availability of diagnostic imaging and radiotherapy equipment in the SEE countries is related to their economic development. While immediate diagnostic imaging and radiation therapy capacity building is necessary, it is also essential to develop both national and SEE-regional cancer registries in order to understand the heterogeneity of each country’s needs and to establish regional collaborative strategies for combating cancer.
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The Spectrum of FANCM Protein Truncating Variants in European Breast Cancer Cases
(MDPI AG, 2020)
Figlioli, Gisella
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Kvist, Anders
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Tham, Emma
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Soukupova, Jana
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Kleiblova, Petra
Germline protein truncating variants (PTVs) in the FANCM gene have been associated with a 2-4-fold increased breast cancer risk in case-control studies conducted in different European populations. However, the distribution and the frequency of FANCM PTVs in Europe have never been investigated. In the present study, we collected the data of 114 European female breast cancer cases with FANCM PTVs ascertained in 20 centers from 13 European countries. We identified 27 different FANCM PTVs. The p.Gln1701* PTV is the most common PTV in Northern Europe with a maximum frequency in Finland and a lower relative frequency in Southern Europe. On the contrary, p.Arg1931* seems to be the most common PTV in Southern Europe. We also showed that p.Arg658*, the third most common PTV, is more frequent in Central Europe, and p.Gln498Thrfs*7 is probably a founder variant from Lithuania. Of the 23 rare or unique FANCM PTVs, 15 have not been previously reported. We provide here the initial spectrum of FANCM PTVs in European breast cancer cases.
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Common variants in breast cancer risk loci predispose to distinct tumor subtypes
(Springer Science and Business Media LLC, 2022-01-04)
Ahearn, Thomas U
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Zhang, Haoyu
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Michailidou, Kyriaki
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Milne, Roger L
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Bolla, Manjeet K
Genome-wide association studies (GWAS) have identified multiple common breast cancer susceptibility variants. Many of these variants have differential associations by estrogen receptor (ER) status, but how these variants relate with other tumor features and intrinsic molecular subtypes is unclear.
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Expenditures on Oncology Drugs and Cancer Mortality-to-Incidence Ratio in Central and Eastern Europe
(Alphamed Press, 2019)
Vrdoljak, Eduard
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Bodoky, Gyorgy
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Jassem, Jacek
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Popescu, Razvan
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Pirker, Robert
There is a steady decline in cancer mortality in Western Europe (WE), but this trend is not so obvious in Central and Eastern Europe (CEE). One of the largest discrepancies between WE and CEE is the level of investment in cancer care. The objective of our analysis was to examine the correlation between mortality-to-incidence (M/I) ratio and expenditures on oncology drugs in CEE and WE.
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Prognostic Factors in Patients with Squamous Cell Carcinoma of the Oral Tongue Treated With Adjuvant Therapy Following Surgery
(Conscientia Beam, 2014)
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The Spectrum of FANCM Protein Truncating Variants in European Breast Cancer Cases
(MDPI AG, 2020)
Figlioli, Gisella
;
Kvist, Anders
;
Tham, Emma
;
Soukupova, Jana
;
Kleiblova, Petra
Germline protein truncating variants (PTVs) in the FANCM gene have been associated with a 2-4-fold increased breast cancer risk in case-control studies conducted in different European populations. However, the distribution and the frequency of FANCM PTVs in Europe have never been investigated. In the present study, we collected the data of 114 European female breast cancer cases with FANCM PTVs ascertained in 20 centers from 13 European countries. We identified 27 different FANCM PTVs. The p.Gln1701* PTV is the most common PTV in Northern Europe with a maximum frequency in Finland and a lower relative frequency in Southern Europe. On the contrary, p.Arg1931* seems to be the most common PTV in Southern Europe. We also showed that p.Arg658*, the third most common PTV, is more frequent in Central Europe, and p.Gln498Thrfs*7 is probably a founder variant from Lithuania. Of the 23 rare or unique FANCM PTVs, 15 have not been previously reported. We provide here the initial spectrum of FANCM PTVs in European breast cancer cases.
Some of the metrics are blocked by your
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Dosimetric comparison of two-dimensional versus three-dimensional intracavitary brachytherapy in locally advanced cervical cancer
(National Library of Serbia, 2018)
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Chakalaroski, Petar
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Dimitrovska, Nadica

Smichkoska, Snezhana

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