Common variants in breast cancer risk loci predispose to distinct tumor subtypes
Journal
Breast cancer research : BCR
Date Issued
2022-01-04
Author(s)
Ahearn, Thomas U
Zhang, Haoyu
Michailidou, Kyriaki
Milne, Roger L
Bolla, Manjeet K
Dennis, Joe
Dunning, Alison M
Lush, Michael
Wang, Qin
Andrulis, Irene L
Anton-Culver, Hoda
Arndt, Volker
Aronson, Kristan J
Auer, Paul L
Augustinsson, Annelie
Baten, Adinda
Becher, Heiko
Behrens, Sabine
Benitez, Javier
Bermisheva, Marina
Blomqvist, Carl
Bojesen, Stig E
Bonanni, Bernardo
Børresen-Dale, Anne-Lise
Brauch, Hiltrud
Brenner, Hermann
Brooks-Wilson, Angela
Brüning, Thomas
Burwinkel, Barbara
Buys, Saundra S
Canzian, Federico
Castelao, Jose E
Chang-Claude, Jenny
Chanock, Stephen J
Chenevix-Trench, Georgia
Clarke, Christine L
Collée, J Margriet
Cox, Angela
Cross, Simon S
Czene, Kamila
Daly, Mary B
Devilee, Peter
Dörk, Thilo
Dwek, Miriam
Eccles, Diana M
Evans, D Gareth
Fasching, Peter A
Figueroa, Jonine
Floris, Giuseppe
Gago-Dominguez, Manuela
Gapstur, Susan M
García-Sáenz, José A
Gaudet, Mia M
Giles, Graham G
Goldberg, Mark S
González-Neira, Anna
Alnæs, Grethe I Grenaker
Grip, Mervi
Guénel, Pascal
Haiman, Christopher A
Hall, Per
Hamann, Ute
Harkness, Elaine F
Heemskerk-Gerritsen, Bernadette A M
Holleczek, Bernd
Hollestelle, Antoinette
Hooning, Maartje J
Hoover, Robert N
Hopper, John L
Howell, Anthony
Jakimovska, Milena
Jakubowska, Anna
John, Esther M
Jones, Michael E
Jung, Audrey
Kaaks, Rudolf
Kauppila, Saila
Keeman, Renske
Khusnutdinova, Elza
Kitahara, Cari M
Ko, Yon-Dschun
Koutros, Stella
Kristensen, Vessela N
Krüger, Ute
Kubelka-Sabit, Katerina
Kurian, Allison W
Kyriacou, Kyriacos
Lambrechts, Diether
Lee, Derrick G
Lindblom, Annika
Linet, Martha
Lissowska, Jolanta
Llaneza, Ana
Lo, Wing-Yee
MacInnis, Robert J
Mannermaa, Arto
Manoochehri, Mehdi
Margolin, Sara
Martinez, Maria Elena
McLean, Catriona
Meindl, Alfons
Menon, Usha
Nevanlinna, Heli
Newman, William G
Nodora, Jesse
Offit, Kenneth
Olsson, Håkan
Orr, Nick
Park-Simon, Tjoung-Won
Patel, Alpa V
Peto, Julian
Pita, Guillermo
Plaseska-Karanfilska, Dijana
Prentice, Ross
Punie, Kevin
Pylkäs, Katri
Radice, Paolo
Rennert, Gad
Romero, Atocha
Rüdiger, Thomas
Saloustros, Emmanouil
Sampson, Sarah
Sandler, Dale P
Sawyer, Elinor J
Schmutzler, Rita K
Schoemaker, Minouk J
Schöttker, Ben
Sherman, Mark E
Shu, Xiao-Ou
Southey, Melissa C
Spinelli, John J
Swerdlow, Anthony J
Tamimi, Rulla M
Tapper, William J
Taylor, Jack A
Teras, Lauren R
Terry, Mary Beth
Torres, Diana
Troester, Melissa A
Vachon, Celine M
van Deurzen, Carolien H M
van Veen, Elke M
Wagner, Philippe
Weinberg, Clarice R
Wendt, Camilla
Wesseling, Jelle
Winqvist, Robert
Wolk, Alicja
Yang, Xiaohong R
Zheng, Wei
Couch, Fergus J
Simard, Jacques
Kraft, Peter
Easton, Douglas F
Pharoah, Paul D P
Schmidt, Marjanka K
García-Closas, Montserrat
Chatterjee, Nilanjan
DOI
10.1186/s13058-021-01484-x
Abstract
Genome-wide association studies (GWAS) have identified multiple common breast cancer susceptibility variants. Many of these variants have differential associations by estrogen receptor (ER) status, but how these variants relate with other tumor features and intrinsic molecular subtypes is unclear.