INCIDENCE AND RISK FACTORS FOR RETINOPATHY OF PREMATURITY

Abstract

ABSTRACT Retinopathy of Prematurity (ROP) is a major cause of preventable blindness in preterm infants. The incidence of ROP is increasing in developing countries due to increased survival of preterm infants. The profile of ROP differs between various countries. Retinopathy of prematurity (ROP) is a serious complication of prematurity and can lead to blindness unless is recognized and treated early The aim of our study was to study the risk factors and the incidence for ROP. A total of 204 infants (37.3% were twins, 2.9% were triplets and 59.8% were singleton) had examination of the retina by indirect ophthalmoscopy from the fourth postnatal week and followed up periodically. Perinatal risk factors for ROP were assessed using univariate and multivariate analysis.204 preterm infants with less of 37 weeks were included. Antenatal, perinatal and postnatal data were collected for all infants. Multiple antenatal, perinatal and postnatal risk factors were identified. ROP was seen in birth weight of 1727 gr. ± 346 and gestational age of 32.8±2.2 weeks. There was significant difference in gestational age and birth weight between preterms infants with and without ROP (p< 0.05). Logistic regression analysis showed that there was a significant relationship between the occurrence of ROP and gestational age, Birth weight, Apgar scor 1min., multiple pregnancy and IVF(in vitro fertilization) (p<0.05) The incidence of ROP was an overall 38.7%.The incidence of ROP in assisted conception- in vitro fertilization were 60.8%, and in a natural way fertilization were 39.2%.The incidences of ROP according gender were 45.6 %-male, and 54.4% female