Complications associated with acute pulmonary embolism – data from the registry of patients with venous thrombembolism
Journal
Македонски Медицински Преглед = Macedonian Medical Review
Date Issued
2022
Author(s)
Dejan Todevski
Suzana Arbutina
Elena Janeva
Abstract
Correct estimation of the severity, mortality, and complication risk are crucial for effective treatment of pulmonary embolism (PE). A total of 162 patients hospitalized with acute PE, treated either with standard treatment with heparin and vitamin K antagonists (VKA) or
heparins, followed by direct oral anticoagulants (DOAC)
were followed for a 90-days period. Demography,
clinical and radiologic presentation, smoking status
and concomitant comorbidities were analyzed. The
mortality risk was estimated by calculating PESI and
sPESI score. The results showed uneven utilization of
both treatment modalities (93.8% treated with VKA
versus 6.17% with DOAC). Smoking as an independent factor was detected in 55.56% of patients, and is
greater than the overall smoking prevalence in Macedonia. Central propagation of PE was found in 57.79%
of cases and together with the presence of pleural effusion was associated with a greater risk for complications. Estimation of 30-day mortality risk with PESI
and sPESI showed their high predictive value, with an
advantage of sPESI, in terms of better accuracy and
simplicity of performance. Correct estimation of risk for
complications and mortality is important for improving
the overall safety of patients with PE and has a positive
„cost-benefit“ effect for organization of the treatment.
heparins, followed by direct oral anticoagulants (DOAC)
were followed for a 90-days period. Demography,
clinical and radiologic presentation, smoking status
and concomitant comorbidities were analyzed. The
mortality risk was estimated by calculating PESI and
sPESI score. The results showed uneven utilization of
both treatment modalities (93.8% treated with VKA
versus 6.17% with DOAC). Smoking as an independent factor was detected in 55.56% of patients, and is
greater than the overall smoking prevalence in Macedonia. Central propagation of PE was found in 57.79%
of cases and together with the presence of pleural effusion was associated with a greater risk for complications. Estimation of 30-day mortality risk with PESI
and sPESI showed their high predictive value, with an
advantage of sPESI, in terms of better accuracy and
simplicity of performance. Correct estimation of risk for
complications and mortality is important for improving
the overall safety of patients with PE and has a positive
„cost-benefit“ effect for organization of the treatment.