A RARE CASE OF SEROUS CARCINOMA OF THE UTERINE CORPUS THAT ARISES IN POLYP

Journal
Journal of Morphological Sciences
Date Issued
2022
Author(s)
Emil Bajalski
Dimitar Georgiev
Bashkim Ismaili
Aleksandar Nakov
DOI
10.55302/JMS2251044k
Abstract
Endometrial polyps (EPs) are common pathological findings and their prevalence range is between
16% to 34% depending on characteristics of the examined population and detecting methods. Clinically,
these lesions cause thickening of the endometrium and abnormal uterine bleeding. Asymptomatic EPs can
be detected by routine ultrasound examination or infertility investigations. Most EPs are benign.
Their malignant potential is highest in postmenopausal women with uterine bleeding (2.3%).
Serous carcinoma is the prototype of type-II endometrial cancer (nonendometrioid) and accounts for <10%
of all endometrial carcinomas.
It is a very aggressive tumor, unrelated to estrogen stimulation, arising occasionally in endometrial
polyps or from precancerous lesions developing in atrophic endometrium that mainly occur in older women.
We present a case of 72-years-old patient with uterine bleeding, with thick and heterogenous
endometrium detected on ultrasound. Fractionated explorative curretage was performed and serous
carcinoma that arises in polyp was diagnosed. After operative treatment, histopathological analysis of the
operative material showed stage II of the disease.
Subjects

endometrial polyps

abnormal uterine blee...

serous carcinoma

endometrial thickeni...

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