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|Title:||Comparison of ZAP-70/Syk mRNA levels with immunoglobulin heavy-chain gene mutation status and disease progression in chronic lymphocytic leukemia||Authors:||Laurenti, Luca
Efremov, Dimitar G
|Issue Date:||Nov-2005||Journal:||Haematologica||Abstract:||The protein tyrosine kinase ZAP-70 has recently emerged as a major prognostic indicator in chronic lymphocytic leukemia (CLL). ZAP-70 is structurally and functionally homologous to Syk, a key mediator of B-cell receptor signaling. We therefore evaluated ZAP-70 expression in CLL B cells using Syk as an intracellular standard.||URI:||http://hdl.handle.net/20.500.12188/1770|
|Appears in Collections:||Faculty of Medicine: Journal Articles|
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