Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12188/16500
Title: DEEP VEIN THROMBOSIS AND RECURENT PULMONARY EMBOLISM IN A PATIENT WITH THROMBOPHILIC MUTATIONS AND GENERALIZED PSORIASIS: A CASE REPORT
Authors: Baloski, Marjan
Buklioska Ilievska, Daniela 
Brishkoska Boshkovski, Vesna
Hasan, Taner
Nedeska Minova, Natasha
Prgova-Veljanova, Biljana 
Nanceva Bogoevska, Andrea
Nancheva, Jasminka 
Bosevski, Marijan 
Panov, Saso
Keywords: recurrent venous thromboembolism
thrombophilia
psoriasis
pulmonary embolism
Issue Date: 29-Jul-2020
Publisher: Association of medical doctors "Sanamed" Novi Pazar
Journal: SANAMED
Abstract: Introduction: Genetic risk factors that increase venous thromboembolism risk are disorders in the synthesis or activity of coagulation factors. Fac- tor V Leiden, prothrombin (20210-A), antithrombin deficiency, protein C and protein S deficiency, and hyperhomocysteinaemia are the most common venous thromboembolism-related gene mutations. When ge- netic factors are combined with non-provoking risk factors (obesity, psoriasis, smoking and previous veno- us thromboembolism) the result is increased venous thromboembolism risk for each factor individually. Previous venous thromboembolism is one of the stron- gest risk factors, even in patients actively treated with anticoagulant. Patients are more likely to have recur- rent venous thromboembolism with longer duration. Psoriasis is a complex immune–mediated disease, as- sociated with cardiovascular risk, hypercoagulability markers and elevated homocysteine. Lots of observati- onal reports suggest increased incidence of venous trombembolic events in patient with psoriasis
URI: http://hdl.handle.net/20.500.12188/16500
DOI: 10.24125/sanamed.v15i2.391
Appears in Collections:Faculty of Medicine: Journal Articles

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