Latent Tuberculosis Infection - Diagnosis and Treatment
Journal
Open Access Macedonian Journal of Medical Sciences
Date Issued
2018-04-15
Author(s)
Ilievska-Poposka, Biljana
Metodieva, Marija
Zakoska, Maja
Vragoterova, Cveta
DOI
10.3889/oamjms.2018.161
Abstract
Latent tuberculosis infection (LTBI) is defined as a state of persistent immune response to stimulation by Mycobacterium tuberculosis antigens without evidence of clinically manifested active tuberculosis (TB). Diagnosis and treatment for LTBI are important for TB, especially in high-risk populations. Tuberculin skin test (TST) and interferon-gamma release assays (IGRAs) are used to diagnose LTBI.