DIAGNOSING ABDOMINAL OBESITY IN WOMEN WITH CUT – OFF POINT VALUES OF THE ESTIMATED CENTRAL OBESITY INDEX DETERMINED WITH DUAL-ENERGY X-RAY ABSORPTIOMETRY
Journal
ACTA MORPHOLOGICA
Date Issued
2020
Author(s)
Abstract
Introduction: Dual-energy X-ray absorptiometric (DXA), central obesity index (COI) and
estimated COI (eCOI) are useful diagnostic DXA test procedures of extreme central, abdominal
obesity in Cushing’s syndrome (CS) and non CS abdominally obese women, and determination
of their diagnostic cut-off point values (CPV) is very important.
Materials and methods: COI and eCOI values were determined in 3 groups, each
consisting of 18 women: 1st group of CS, 2nd group of obese women (O) not different according
to their age and Body Mass Index (BMI) with CS and 3rd group of non-obese healthy women
(C) with normal BMI. COI1 and eCOI1 CPV were used to best differentiate CS and O. COI2
and eCOI2 CPV were used to best differentiate CS and O with C. Their diagnostic accuracy
(DG), sensitivity (S) and specificity (SP) were determined.
Results: COI and eCOI values were significantly different among the 3 groups. COI1 CPV
of 0.9 best differentiated CS from O with DG of 70% and sensitivity of 90% but eCOI1 CPV
of 0.92 differentiated them with DG of 75% and S of 100%.
COI2 CPV of 0.82 best differentiated C from O with DG of 82.14% and SP of 88.89% as
well as eCOI2 CPV of 0.84 differentiated them for DG of 75% and SP of 80%. COI2 CPV of
0.82 and eCOI2 0.84 best differentiated CS from C in both cases for DG of 92.86% and SP of
88.89%.
Conclusion: Cut-off point values of COI1 and COI2 as well as eCOI1 and eCOI2 are very
important diagnostic test procedures in discovering abdominal and normal body fat
distribution. Determined eCOI1 and eCOI2 cut-off point values are especially very useful
diagnostic screening tests of body fat distribution in everyday routine clinical praxis during
spine and hip bone mineral content assessment.
estimated COI (eCOI) are useful diagnostic DXA test procedures of extreme central, abdominal
obesity in Cushing’s syndrome (CS) and non CS abdominally obese women, and determination
of their diagnostic cut-off point values (CPV) is very important.
Materials and methods: COI and eCOI values were determined in 3 groups, each
consisting of 18 women: 1st group of CS, 2nd group of obese women (O) not different according
to their age and Body Mass Index (BMI) with CS and 3rd group of non-obese healthy women
(C) with normal BMI. COI1 and eCOI1 CPV were used to best differentiate CS and O. COI2
and eCOI2 CPV were used to best differentiate CS and O with C. Their diagnostic accuracy
(DG), sensitivity (S) and specificity (SP) were determined.
Results: COI and eCOI values were significantly different among the 3 groups. COI1 CPV
of 0.9 best differentiated CS from O with DG of 70% and sensitivity of 90% but eCOI1 CPV
of 0.92 differentiated them with DG of 75% and S of 100%.
COI2 CPV of 0.82 best differentiated C from O with DG of 82.14% and SP of 88.89% as
well as eCOI2 CPV of 0.84 differentiated them for DG of 75% and SP of 80%. COI2 CPV of
0.82 and eCOI2 0.84 best differentiated CS from C in both cases for DG of 92.86% and SP of
88.89%.
Conclusion: Cut-off point values of COI1 and COI2 as well as eCOI1 and eCOI2 are very
important diagnostic test procedures in discovering abdominal and normal body fat
distribution. Determined eCOI1 and eCOI2 cut-off point values are especially very useful
diagnostic screening tests of body fat distribution in everyday routine clinical praxis during
spine and hip bone mineral content assessment.
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