Invasive vs Conservative Management of Patients With Chronic Total Occlusion: Results From the ISCHEMIA Trial

Journal

Journal of the American College of Cardiology

Date Issued

2025-04-01

Author(s)

Bangalore, Sripal

Mancini, G B John

Leipsic, Jonathan

Budoff, Mathew J

Xu, Yifan

Anthopolos, Rebecca

Brilakis, Emmanouil S

Dwivedi, Aeshita

Spertus, John A

Jones, Phil G

Cho, Yoon Joo

Mark, Daniel B

Hague, Cameron J

Min, James K

Reynolds, Harmony R

Elghamaz, Ahmed

Nair, Rajesh Goplan

Mavromatis, Kreton

Gosselin, Gilbert

Banerjee, Subhash

Lindsay, Steven

Grantham, J Aaron

Williams, David O

Stone, Gregg W

O'Brien, Sean M

Hochman, Judith S

Maron, David J

DOI

10.1016/j.jacc.2025.01.029

Abstract

Randomized trials of chronic total occlusion (CTO) revascularization vs medical therapy have yielded inconsistent results.