Reliable and durable Golgi staining of brain tissue from human autopsies and experimental animals
Journal
Journal of Neuroscience Methods
Date Issued
2014-06-15
Author(s)
Rosoklija, Gorazd B
Petrushevski, Vladimir M
Dika, Ani
Lipkin, Richard
Schnieder, Tatiana
Scobie, Kimberley
Duma, Aleksej
Dwork, Andrew J
DOI
10.1016/j.jneumeth.2014.04.006
Abstract
Golgi stains are notoriously capricious, particularly when applied to human brain. The well-known difficulties, which include complete failure of impregnation, patchy staining, unstable staining, and extensive crystalline deposits in superficial sections, have discouraged many from attempting to use these techniques. A reliable method that produces uniform impregnation in tissue from human autopsies and experimental animals is needed.