Intraoperative positive end-expiratory pressure and postoperative pulmonary complications: a patient-level meta-analysis of three randomised clinical trials

Journal
British Journal of Anaesthesia
Date Issued
2022-06
Author(s)
Campos, Niklas S
Bluth, Thomas
Hemmes, Sabrine N T
Librero, Julian
Pozo, Natividad
Ferrando, Carlos
Ball, Lorenzo
Mazzinari, Guido
Pelosi, Paolo
Gama de Abreu, Marcelo
Schultz, Marcus J
Serpa Neto, A
PROBESE Study Group
DOI
10.1016/j.bja.2022.02.039
Abstract
High intraoperative PEEP with recruitment manoeuvres may improve perioperative outcomes. We re-examined this question by conducting a patient-level meta-analysis of three clinical trials in adult patients at increased risk for postoperative pulmonary complications who underwent non-cardiothoracic and non-neurological surgery.
Subjects

mechanical ventilatio...

PEEP

postoperative pulmona...

surgery

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