Platelet-rich plasma as a promising bioscaffold for enhancing peripheral nerve regeneration: An experimental study in a rat sciatic nerve model

Pejkova, Sofija; Stojkovski, Velimir; Georgieva, Gordana; Aleksovski, Boris; Tusheva, Sofija; Srbov, Blagoja; Rafailovska, Elena; Mladenovska, Stefania Azmanova; Jovanovska, Katerina; Nikolovska, Bisera; Ilievski, Boro; DZonov, Boro; Ristoski, Trpe; Petrushevska, Anita; GJorgoski, Icko

doi:10.14440/jbm.2025.0083

Platelet-rich plasma as a promising bioscaffold for enhancing peripheral nerve regeneration: An experimental study in a rat sciatic nerve model

Journal

Journal of biological methods

Date Issued

2025

Author(s)

Aleksovski, Boris

Tusheva, Sofija

Rafailovska, Elena

Mladenovska, Stefania Azmanova

Jovanovska, Katerina

Petrushevska, Anita

DOI

10.14440/jbm.2025.0083

Abstract

Despite advancements in surgical treatments, impairments persist after peripheral nerve injuries, prompting a shift in research toward the microenvironment of injured axons. Platelet-rich plasma (PRP), rich in growth factors and derived from autologous blood, emerges as a potential candidate to accelerate nerve healing.