LARGE NECK TERATOMA IN A NEWBORN WITH RESPIRATORY DISTRESS SYNDROME
Journal
Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki)
Date Issued
2021-04
Author(s)
Goran Kocovski
Abstract
Neonatal tumours in the neck region are a rare finding. Teratomas typically comprise all three germ cell
layers with tissues usually foreign to the anatomic site of origin. Head and neck teratomas account a
smaller part of congenital teratomas. They can cause major airway obstruction due to the external compression that oropharyngeal or neck masses produce. In addition, there can be an intrinsic lesion in the
larynx or trachea. We describe a premature, 30-gestational week-old newborn with large subcutaneous
neck mass. Pre-delivery ultrasound showed heterogeneous tumor structure and displaced larynx. The
intubation was successful. The newborn developed respiratory distress syndrome immediately after
birth which rendered the surgical removal of the neck tumor impossible. An autopsy was done, and the
histopathology revealed mature teratoma comprising muscle, brain, salivary and pulmonary tissues, as
well as well-developed hyaline membranes in the alveoli. The combination of the respiratory distress
syndrome and the neck tumor compression proved fatal. Prenatal diagnosis, therapeutic options and
ex utero intrapartum treatment (EXIT) procedures are discussed for the diagnosis and management of
this very rare tumor.
layers with tissues usually foreign to the anatomic site of origin. Head and neck teratomas account a
smaller part of congenital teratomas. They can cause major airway obstruction due to the external compression that oropharyngeal or neck masses produce. In addition, there can be an intrinsic lesion in the
larynx or trachea. We describe a premature, 30-gestational week-old newborn with large subcutaneous
neck mass. Pre-delivery ultrasound showed heterogeneous tumor structure and displaced larynx. The
intubation was successful. The newborn developed respiratory distress syndrome immediately after
birth which rendered the surgical removal of the neck tumor impossible. An autopsy was done, and the
histopathology revealed mature teratoma comprising muscle, brain, salivary and pulmonary tissues, as
well as well-developed hyaline membranes in the alveoli. The combination of the respiratory distress
syndrome and the neck tumor compression proved fatal. Prenatal diagnosis, therapeutic options and
ex utero intrapartum treatment (EXIT) procedures are discussed for the diagnosis and management of
this very rare tumor.
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