THE ASSOCIATION OF SQUAMOUS KERATINIZING METAPLASIA (LEUKOPLAKIA) OF THE BLADDER WITH SYMPTOMS OF THE LOWER URINARY TRACT IN WOMEN
Journal
Уронет (Конгресен брой)
Date Issued
2024
Author(s)
Abstract
INTRODUCTION:
Squamous keratinizing metaplasia (SCM) of the
bladder, also known as leukoplakia of the bladder,
is a condition in which the normal transitional
epithelium is transformed into a squamous
epithelium overlying a layer of keratin (1). In most
patients, typical non-specific urinary symptoms
are expressed, such as frequency, urgency,
suprapubic pain, discomfort, microhematuria and,
less often, macrohematuria (7).
OBJECTIVES OF THE STUDY:
- To prove the relationship between bladder
leukoplakia and urinary symptoms in affected
women.
- To determine the effect of endoscopic
resection of leukoplakia in relation to conservative
treatment
MATERIALS AND METHODS:
The study analysed 50 patients with long term lower urinary tract symptoms (more than
six months) between 2021 and July 2024. All
underwent cystoscopy. The study included
patients with a pathohistological diagnosis of
squamous keratinizing metaplasia of the bladder.
The severity of symptoms was determined
according to the international classification for
urinary symptoms (International prostate symptom
score - IPSS). Bi-polar transurethral resection of
squamous keratinizing metaplasia of the bladder
was performed in all patients. One month after
the intervention, the patients were called for a
follow-up examination, during which the severity
of urinary symptoms was re-evaluated according
to the IPSS. Then a comparative analysis was
performed, on the basis of which the significant
difference of IPSS before and after the intervention
was assessed.
RESULTS:
Of the total number of female patients, lower
urinary tract symptoms, pain and hematuria
were the most common symptoms. After the
intervention there was a significant improvement
in the initial IPSS score. The percentage of
patients with severe and moderate lower urinary
tract symptoms decreased from 57.1% to 25.7%.
No hematuria was reported, and most of the
patients reported an improvement in their quality
of life. A total of 64.4% of patients reported an
improvement in symptoms, in 23.5% there was no
improvement, and 12.1% reported worsening of
symptoms.
CONCLUSION:
Bipolar transurethral resection significantly
relieves symptoms in women with squamous
keratinizing metaplasia, improves quality of
life according to the IPSS questionnaire by an
acceptable 64.4%, and is superior to conservative
treatment
Squamous keratinizing metaplasia (SCM) of the
bladder, also known as leukoplakia of the bladder,
is a condition in which the normal transitional
epithelium is transformed into a squamous
epithelium overlying a layer of keratin (1). In most
patients, typical non-specific urinary symptoms
are expressed, such as frequency, urgency,
suprapubic pain, discomfort, microhematuria and,
less often, macrohematuria (7).
OBJECTIVES OF THE STUDY:
- To prove the relationship between bladder
leukoplakia and urinary symptoms in affected
women.
- To determine the effect of endoscopic
resection of leukoplakia in relation to conservative
treatment
MATERIALS AND METHODS:
The study analysed 50 patients with long term lower urinary tract symptoms (more than
six months) between 2021 and July 2024. All
underwent cystoscopy. The study included
patients with a pathohistological diagnosis of
squamous keratinizing metaplasia of the bladder.
The severity of symptoms was determined
according to the international classification for
urinary symptoms (International prostate symptom
score - IPSS). Bi-polar transurethral resection of
squamous keratinizing metaplasia of the bladder
was performed in all patients. One month after
the intervention, the patients were called for a
follow-up examination, during which the severity
of urinary symptoms was re-evaluated according
to the IPSS. Then a comparative analysis was
performed, on the basis of which the significant
difference of IPSS before and after the intervention
was assessed.
RESULTS:
Of the total number of female patients, lower
urinary tract symptoms, pain and hematuria
were the most common symptoms. After the
intervention there was a significant improvement
in the initial IPSS score. The percentage of
patients with severe and moderate lower urinary
tract symptoms decreased from 57.1% to 25.7%.
No hematuria was reported, and most of the
patients reported an improvement in their quality
of life. A total of 64.4% of patients reported an
improvement in symptoms, in 23.5% there was no
improvement, and 12.1% reported worsening of
symptoms.
CONCLUSION:
Bipolar transurethral resection significantly
relieves symptoms in women with squamous
keratinizing metaplasia, improves quality of
life according to the IPSS questionnaire by an
acceptable 64.4%, and is superior to conservative
treatment
File(s)![Thumbnail Image]()
Loading...
Name
uronet-02-2024, darko.pdf
Size
458.22 KB
Format
Adobe PDF
Checksum
(MD5):db7e689818d942306f7431a7968216b6