Influence of gender, inheritance factor and age in glaucoma occurrence and progress
Journal
Medicus
Date Issued
2020
Author(s)
DOI
http://www.medalb.com/revista/medicus-dhjetor-2020.pdf
Abstract
INTRODUCTION: Glaucoma, one of the leading causes of irreversible blindness in the elderly population worldwide,
is a progressive optic neuropathy. Risk factors for glaucoma have been explored and published in many studies.
Elevated intraocular pressure (IOP) is, as is well known, the highest risk for glaucoma. Studies show that reducing
IOP reduces the risk of developing the disease or slows the progression of glaucoma. There is growing evidence that
other risk factors such as age, sex, race, refraction, heredity, and systemic diseases play a role in the pathogenesis
of glaucoma.
The risk factors for glaucoma can be divided into systemic and local. Systemic risk factors are blood pressure:
hypotension or hypertension, vasospasm, diabetes, chronic heart disease, hypercholesterolemia, thyroid disease,
etc. Local risk factors are parapapillary atrophy, intraocular pressure, papillary excavation, certain diseases of the
anterior or posterior segment of the eye, central corneal thickness, fluctuations in IOP, etc.
RESOURCES AND METHODS: A case-control study was performed, which included patients aged 25 to 70.The study
was conducted at the Clinic for Eye Diseases, in Skopje, in the Glaucoma Cabinet, in the period from 2015-2019.The
study included 100 patients, who were divided into two groups. About the patients in the study, a comprehensive
medical history was made, as well as a history of the condition, age, sex, family history, hereditary factor, and
whether the patient was using anti glaucoma therapy.
RESULTS: In determining the significance of the contribution to the prediction of glaucoma, it was found that the
age of the patients had the greatest influence (Wald = 5.05 / p <0.05 (p = 0.025), followed by the family history (Wald
= 0.04 / p> 0 , 05 (p = 0.84) and the weakest is the influence of the sex of the patients (Wald = 0.01 / p> 0.05 (p = 0.94)
is a progressive optic neuropathy. Risk factors for glaucoma have been explored and published in many studies.
Elevated intraocular pressure (IOP) is, as is well known, the highest risk for glaucoma. Studies show that reducing
IOP reduces the risk of developing the disease or slows the progression of glaucoma. There is growing evidence that
other risk factors such as age, sex, race, refraction, heredity, and systemic diseases play a role in the pathogenesis
of glaucoma.
The risk factors for glaucoma can be divided into systemic and local. Systemic risk factors are blood pressure:
hypotension or hypertension, vasospasm, diabetes, chronic heart disease, hypercholesterolemia, thyroid disease,
etc. Local risk factors are parapapillary atrophy, intraocular pressure, papillary excavation, certain diseases of the
anterior or posterior segment of the eye, central corneal thickness, fluctuations in IOP, etc.
RESOURCES AND METHODS: A case-control study was performed, which included patients aged 25 to 70.The study
was conducted at the Clinic for Eye Diseases, in Skopje, in the Glaucoma Cabinet, in the period from 2015-2019.The
study included 100 patients, who were divided into two groups. About the patients in the study, a comprehensive
medical history was made, as well as a history of the condition, age, sex, family history, hereditary factor, and
whether the patient was using anti glaucoma therapy.
RESULTS: In determining the significance of the contribution to the prediction of glaucoma, it was found that the
age of the patients had the greatest influence (Wald = 5.05 / p <0.05 (p = 0.025), followed by the family history (Wald
= 0.04 / p> 0 , 05 (p = 0.84) and the weakest is the influence of the sex of the patients (Wald = 0.01 / p> 0.05 (p = 0.94)
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