Chlorhexidine versus povidone-iodine skin antisepsis before upper limb surgery (CIPHUR): an international multicentre prospective cohort study

Wade, Ryckie G; Bourke, Gráinne; Wormald, Justin C R; Totty, Joshua Philip; Stanley, Guy Henry Morton; Lewandowski, Andrew; Rakhra, Sandeep Singh; Gardiner, Matthew D; Pejkova, Sofija; Georgieva, Gordana; Nikolovska, Bisera; Srbov, Blagoja

doi:10.1093/bjsopen/zrab117

Chlorhexidine versus povidone-iodine skin antisepsis before upper limb surgery (CIPHUR): an international multicentre prospective cohort study

Journal

BJS open

Date Issued

2021-11-09

Author(s)

Wade, Ryckie G

Bourke, Gráinne

Wormald, Justin C R

Totty, Joshua Philip

Stanley, Guy Henry Morton

Lewandowski, Andrew

Rakhra, Sandeep Singh

Gardiner, Matthew D

Georgieva, Gordana

Srbov, Blagoja

DOI

10.1093/bjsopen/zrab117

Abstract

Surgical site infection (SSI) is the most common and costly complication of surgery. International guidelines recommend topical alcoholic chlorhexidine (CHX) before surgery. However, upper limb surgeons continue to use other antiseptics, citing a lack of applicable evidence, and concerns related to open wounds and tourniquets. This study aimed to evaluate the safety and effectiveness of different topical antiseptics before upper limb surgery.

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