HISTOPATHOLOGICAL FINDINGS IN PATIENTS WITH ULTRASONOGRAPHICALLY DETECTED ENDOMETRIAL POLYP
Date Issued
2025-09
Author(s)
Bekim Dika
Ivan Koprivnjak
Abstract
Introduction. Endometrial polyps are defined as the excess hyperplastic growth of
endometrial glands and stroma within the uterine cavity. They vary in size from a few
millimeters to several centimeters. Polyps may be found as a single lesion or multiple
lesions filling the entire endometrial cavity. Endometrial polyps may be diagnosed at
all ages but the highest incidence is between 40 - 49 years of age. They are
considered benign but there is a small risk of malignant transformation. Thе aim of
this study is to determine the correlation between the ultrasound findings of
endometrial polyp and the histopathological reports.
Material and methods. We analized a total of 140 histopathological reports from
patients who underwent fractionated explorative curettage or hysteroscopy due to
ultrasonographically diagnosed endometrial polyps. The histopathological findings
showed that in 112 (80%) the diagnosis of endometrial polyp was confirmed and 78
of these were hyperplastic polyps (69.6% of the total number of endometrial polyps),
5 polyps with atypical hyperplasia (4.5%), 1 (0.9%) malignant polyp
(adenocarcinoma), 5 senile polyps (4,5%). Endocervical or isthmicocervical polyp
were diagnosed in 12 patients (8.6%). The remaining 28 patients (20%) had these
findings: simplex endometrial hyperplasia without atypia (6 patients), complex
endometrial hyperplasia without atypia (1), complex endometrial hyperplasia with
atypia (1 patient), submucosal myoma (3), adenomyoma (1), prolonged and
inadequate estrogen action (8), deficient secretory phase (3), chronic cervicitis (3),
and normal endometrium in 2 patients.
Conclusion: Transvaginal ultrasound is the first line of investigation while evaluating
the endometrium. Its accuracy is limited in the diagnosis of focal endometrial
lesions, so the further investigation is needed. Hysteroscopy is the gold standard for
accurate evaluation of intracavitary pathology like submucous fibroid, polyps or
anomalies.
endometrial glands and stroma within the uterine cavity. They vary in size from a few
millimeters to several centimeters. Polyps may be found as a single lesion or multiple
lesions filling the entire endometrial cavity. Endometrial polyps may be diagnosed at
all ages but the highest incidence is between 40 - 49 years of age. They are
considered benign but there is a small risk of malignant transformation. Thе aim of
this study is to determine the correlation between the ultrasound findings of
endometrial polyp and the histopathological reports.
Material and methods. We analized a total of 140 histopathological reports from
patients who underwent fractionated explorative curettage or hysteroscopy due to
ultrasonographically diagnosed endometrial polyps. The histopathological findings
showed that in 112 (80%) the diagnosis of endometrial polyp was confirmed and 78
of these were hyperplastic polyps (69.6% of the total number of endometrial polyps),
5 polyps with atypical hyperplasia (4.5%), 1 (0.9%) malignant polyp
(adenocarcinoma), 5 senile polyps (4,5%). Endocervical or isthmicocervical polyp
were diagnosed in 12 patients (8.6%). The remaining 28 patients (20%) had these
findings: simplex endometrial hyperplasia without atypia (6 patients), complex
endometrial hyperplasia without atypia (1), complex endometrial hyperplasia with
atypia (1 patient), submucosal myoma (3), adenomyoma (1), prolonged and
inadequate estrogen action (8), deficient secretory phase (3), chronic cervicitis (3),
and normal endometrium in 2 patients.
Conclusion: Transvaginal ultrasound is the first line of investigation while evaluating
the endometrium. Its accuracy is limited in the diagnosis of focal endometrial
lesions, so the further investigation is needed. Hysteroscopy is the gold standard for
accurate evaluation of intracavitary pathology like submucous fibroid, polyps or
anomalies.
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