Thrombus Aspiration in Patients With High Thrombus Burden in the TOTAL Trial

Jolly, Sanjit S; Cairns, John A; Lavi, Shahar; Cantor, Warren J; Bernat, Ivo; Cheema, Asim N; Moreno, Raul; Kedev Sasko; Stankovic, Goran; Rao, Sunil V; Meeks, Brandi; Chowdhary, Saqib; Gao, Peggy; Sibbald, Matthew; Velianou, James L; Mehta, Shamir R; Tsang, Michael; Sheth, Tej; Džavík, Vladimír

doi:10.1016/j.jacc.2018.07.047

Thrombus Aspiration in Patients With High Thrombus Burden in the TOTAL Trial

Journal

Journal of the American College of Cardiology

Date Issued

2018

Author(s)

Jolly, Sanjit S

Cairns, John A

Lavi, Shahar

Cantor, Warren J

Bernat, Ivo

Cheema, Asim N

Moreno, Raul

Stankovic, Goran

Rao, Sunil V

Meeks, Brandi

Chowdhary, Saqib

Gao, Peggy

Sibbald, Matthew

Velianou, James L

Mehta, Shamir R

Tsang, Michael

Sheth, Tej

Džavík, Vladimír

DOI

10.1016/j.jacc.2018.07.047

Abstract

Routine thrombus aspiration in patients undergoing primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) does not improve clinical outcomes. However, there is remaining uncertainty about the potential benefit in those patients with high thrombus burden, where there is a biological rationale for greater benefit.