Old syndrome-new approach: Mauriac syndrome treated with continuous insulin delivery

Mirjana Kocova; Liljana Milenkova

doi:10.1177/2050313X18785510

Old syndrome-new approach: Mauriac syndrome treated with continuous insulin delivery

Journal

SAGE Open Medical Case Reports

Date Issued

2018

Author(s)

Liljana Milenkova

DOI

10.1177/2050313X18785510

Abstract

Mauriac syndrome has rarely been reported in children and adolescents with a poorly controlled diabetes mellitus type 1. However, it still occurs despite the worldwide improvements of metabolic control. The risks have not been elucidated. We present a 13.5-year-old boy with a typical clinical presentation of Mauriac syndrome consisting of growth delay, cushingoid appearance, hepatomegaly, and delayed puberty. A stepwise correction of glycemic control was introduced using continuous insulin delivery. All symptoms improved during the 2.5-year follow-up. No retinopathy occurred. This patient with Mauriac syndrome followed with continuous glucose monitoring and treated with continuous insulin delivery, resulting in no retinopathy after 2.5 years of follow-up. We suggest that this approach should be recommended in patients with Mauriac syndrome.