Faculty of Medicine
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Item type:Publication, PREVALENCE AND CHARACTERISTICS OF CHRONIC RESPIRATORY SYMPTOMS AND LUNG FUNCTION AMONG VINEYARD WORKERS(Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, 2025-12-16); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, BODY COMPOSITION AND RESPIRATORY PARAMETER ANALYSIS AT FOOTBALL PLAYERS(ANTHROPOLOGICAL SOCIETY OF SERBIA, 2023-09-27); ; ; ; Pulmonary function tests (PFTs) are commonly used for evaluating respiratory status and managing persons with known pulmonary disease. They have become part of routine health examinations in respiratory, occupational, and sports medicine, and in public-health screening. The results of PFTs are interpreted in relation to normal range reference values, as recommended by the guidelines of the American Thoracic Society (ATS) and the European Community forCoal and Steel (ECCS). Spirometry is a gold standard pulmonary function test that measureshow an individual inhales or exhales volumes of air as a function of time. It is the mostimportant and most frequently performed pulmonary function testing procedure, having becomeindispensable for the prevention, diagnosis, and evaluation of various respiratory impairments. Anumber of 61 football players were divided into 2 groups according to their age, 13 (13.85 ± 3.26) and27 years (23.82 ± 3.32). This study was organized by the Institute of Medical, Experimentaland Applied Physiology and Anthropology, Medical faculty – UKIM, Skopje. The spirometry method was performed with the Spirobank II spirometer (Rome, Italy), for the followingparameters: forced vital capacity (FVC), forced expiratory volume in the first second (FEV1),and the ratio FEV1/FVC ratio.Body composition analyzer InBody 720, Great Britain, was usedto determine body weight (kg), body height (cm), body mass index - BMI weight (kg / m 2 ),skeletal muscle mass SMM (kg) and the amount of proteins (kg) and minerals (kg). We did notfind any statistically significant differences for forced vital capacity (FVC), forced expiratoryvolume in the first second (FEV1), and the ratio FEV1/FVC ratio. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, COPD IN A SAMPLE OF GENERAL ADULT POPULATION FROM THE SKOPJE REGION(University Ss. Cyril and Methodius in Skopje, 2022); ; ; ; Atanasovska, AnetaIntroduction. Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity, disability and mortality in the last decades worldwide. Aim of the study. To determine the COPD prevalence in a sample of general adult population from the Skopje region and its distribution by sex, age, smoking status, working status, family history of chronic bronchitis/asthma, and mode of household heating and cooking. Methods. A cross-sectional study (prevalence study) including 2,348 participants (1,239 males and 1,109 females, aged 18 to 86 years) from the Skopje region was performed at the Institute for Occupational Health of RN Macedonia, Skopje, in the period 2018-2021. The study protocol included completion of a questionnaire and spirometric measurements (pre and post-bronchodilator spirometry). COPD was defined by spirometric finding of persistent airflow limitation in symptomatic study subjects. Results. COPD prevalence in the whole study sample was 4.6%, being non-significantly higher in men (5.1%) than in women (4.1%). Fourfold higher prevalence of COPD was registered in the study subjects aged over 45 years as compared to the younger ones (6.7% vs. 1.6%; P = 0.000). COPD prevalence was significantly higher in active smokers as compared to non-smoking study subjects (9.4% vs. 1.9%; P = 0.000). In regard to working status, COPD prevalence among active workers was 3.9%, in the group of retired persons 8.7%, while in the group of students there was not a single subject with COPD. In addition, COPD prevalence in the workers occupationally exposed to noxious particles or gases was significantly higher than in unexposed workers (4.7% vs. 2.4%; P = 0.021). There was no statistically significant difference in the COPD prevalence between study subjects with positive and negative family history of asthma/chronic bronchitis (4.8% vs. 4.5%), as well as between study subjects who used biomass fuels for heating and cooking (6.2%) and those who did not use traditional fuels for household needs (4.0%). Conclusion. Our findings have indicated the age, active smoking and occupational exposures to noxious particles or gases as the factors significantly related to COPD prevalence in the examined sample of general adult population from the Skopje region. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Lung Function Impairment in Construction Workers – Influence of Smoking and Exposure Duration(Scientific Foundation SPIROSKI, 2021-05-08); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Respiratory Symptoms and Ventilatory Function in Never-Smoking Males Working in Dusty Occupations(ID Design Press, 2014-12-15); AIM: To assess the effect of occupational exposure on respiratory symptoms and ventilatory capacity in never-smoking male workers exposed to mineral or organic dusts.MATERIAL AND METHODS: We performed a cross-sectional study including 138 never-smoking male workers exposed to mineral or organic dust (34 construction workers, 32 furniture manufacturers, 37 agricultural workers, and 35 bakers) and 35 unexposed controls (office workers). Evaluation of all study subjects included completion of a questionnaire and spirometric measurements.RESULTS: The prevalence of the overall respiratory symptoms in the last 12 months was higher in dusty occupation workers than its prevalence in office workers. Statistically significant difference was found between the prevalence of cough in construction workers, agricultural workers and bakers, as well as between the prevalence of phlegm in construction workers, furniture manufacturers and agricultural workers as compared to its prevalence in office workers. The mean values of spirometric parameters were lower in all groups of exposed workers as compared to their mean values in office workers with statistical significance for all measured parameters in construction workers and furniture manufacturers, as well as for small airways indices in agricultural workers and bakers.CONCLUSION: Our findings indicate significant effect of occupational exposure on respiratory symptoms and ventilatory capacity impairment in workers exposed to mineral or organic dusts.</jats:p> - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Chronic obstructive pulmonary disease in never-smoking dairy farmers(2015); ; ; Work-related chronic obstructive pulmonary disease (COPD) represents a considerable part of the disease burden globally. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, C-Reactive Protein Concentrations Among Crop and Dairy Farmers with Stable Chronic Obstructive Pulmonary Disease(ID Design 2012/DOOEL Skopje, Republic of Macedonia, 2017-09-09); ; ; ; Lütfiye TutkunAIM: To assess the mean serum C-reactive protein concentrations among farmers and office controls, and further examined its relation to exposure duration, smoking habit, as well as presence or absence of COPD. METHODS: A cross-sectional survey was performed including examined group (EG), composed of agricultural workers (87 crop - EG1 and 83 dairy farmers - EG2), and control group (CG) composed by 80 office workers. Evaluation of subjects included a questionnaire on chronic respiratory symptoms, lung function tests, COPD diagnostics, and measurement of CRP serum concentrations. RESULTS: Serum CRP concentrations were raised in stable COPD patients independent of smoking habit or exposure duration. The mean CRP serum concentrations were higher in the subjects of EG1 and EG2 compared with those in CG, but without statistical significance. This count for mean CRP serum concentrations in subjects of EG1 and EG2 exposed more than 20 years and for those in smokers in all three groups as well. The mean CRP serum concentrations were significantly higher in subjects with COPD within EG1 (P=0.049) and EG2 (P=0.040), while those in CG were not. CONCLUSION: Data obtained suggest that systemic inflammation is present in farmers with COPD and CRP is an important biomarker in COPD in means of reflecting disease severity and prognosis of exposed farmers.