Faculty of Medicine

Permanent URI for this communityhttps://repository.ukim.mk/handle/20.500.12188/14

Browse

Settings

Subject: search.filters.subject.risk

Search Results

Now showing 1 - 2 of 2
  • Loading...
    Thumbnail Image
    Some of the metrics are blocked by your 
    consent settings
    Item type:Publication,
    Болести на зависност како ризичен предизвик во адолесценцијата
    (Меѓународен центар за славјанска просвета - Свети Николе, 2021)
    ;
    Stoilkovska, Anita
    Adolescence as a developmental period is vulnerable in many aspects. Such vulnerability makes adolescents susceptible to developing addictive diseases. The research was conducted by examining 100 users of the Center for Addictions, PHI General Hospital Kumanovo with a questionnaire application. The obtained results speak in favor of the first contact with psychoactive substances and the initial regular use of psychoactive substances during adolescence, with the highest frequency in post-adolescence/early maturity (18-21 years) and peak around 19 years of age. The discussion compares the results with other official results and makes recommendations for the period for prevention and early detection strategies.
  • Loading...
    Thumbnail Image
    Some of the metrics are blocked by your 
    consent settings
    Item type:Publication,
    Development of a Risk Prediction Score for Occult Cancer in Patients With VTE
    (Elsevier, 2016)
    Jara-Palomares L,
    ;
    Otero R,
    ;
    Jimenez D,
    ;
    Carrier M,
    ;
    Tzoran I,
    Background: The benefits of a diagnostic workup for occult cancer in patients with VTE are controversial. Our aim was to provide and validate a risk score for occult cancer in patients with VTE. Methods: We designed a nested case-control study in a cohort of patients with VTE included in the RIETE (Registro Informatizado Enfermedad TromboEmbólica) registry from 2001 to 2014. Cases included cancer detected beyond the first 30 days and up to 24 months after VTE. Control subjects were defined as patients with VTE with no cancer in the same period. Results: Of 5,863 eligible patients, 444 (7.6%; 95% CI, 6.8%-8.2%) were diagnosed with occult cancer. On multivariable analysis, variables selected were male sex, age > 70 years, chronic lung disease, anemia, elevated platelet count, prior VTE, and recent surgery. We built a risk score assigning points to each variable. Internal validity was confirmed using bootstrap analysis. The proportion of patients with cancer who scored ≤ 2 points was 5.8% (241 of 4,150) and that proportion in those who scored ≥ 3 points was 12% (203 of 1,713). We also identified scores divided by sex and age subgroups. Conclusions: This is the first risk score that has identified patients with VTE who are at increased risk for occult cancer. Our score needs to be externally validated.