Faculty of Medicine

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    TREATMENT OF LYMPHATIC MALFORMATIONS IN CHILDREN: 3 YEARS EXPERIENCE
    (University of Tetovo, 2023-05)
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    Njomza LUMANI-BAKIJI
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    Lazo JOVCHESKI
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    Aleksandar STEPANOVSKI
    Introduction: Lymphatic malformations (LM) are congenital benign malformations from the group of slow-flow vascular anomalies consisting of pathological cystic dilatation of the lymphatic vessels. The incidence of LM ranges from 1.5 to 2.8% in 2000 to 4000 newborn children, and are relatively rare congenital vascular anomalies. They are characterized with equal representation between the genders. From the structural aspect, LM are divided into macrocystic, microcystic and mixed type, with its own therapeutic and prognostic implications. A small percentage of LM are combined with additional anomalies and are part of syndromes such as CLOVES, Klippel-Trenaunay, Proteus and others. In recent years, the method of choice in the treatments is sclerosing as a non-invasive method achieving almost excellent results.
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    EVALUATION OF RESPIRATORY FAILURE FOLLOWING PEDIATRIC CARDIAC SURGERY
    (Macedonian Association of Anatomists and Morphologists, 2021-08)
    Background: This study evaluated the respiratory failure (postoperative reintubation, respiratory acidosis, deterioration of gas blood, respiratory disfunctions, hypoxia) after congenital heart surgery. Material and methods: To evaluate the impact of respiratory failure (within 48 hours postoperatively) in patients undergoing congenital heart surgery. This retrospective study included 45 operated patients (male and female aged 3 to 9 months) who had undergone cardiac surgery at the University Clinic for Pediatric Surgery in a period of two years. Type of congenital heart diseases, perioperative and postoperative parameters (duration of cardiopulmonary bypass - CPB, cross-clamping of aorta, duration of stay in ICU and complications) were analyzed. Results: Of a total of 45 operated patients, five required reintubation, and their average age was 7.5 months, and median body weight 7.8 kg. Perioperative procedures were prolonged (duration of CPB - 97 minutes, aortic cross-clamping time - 59 min. and duration stay in ICU -7.2 days), caused postoperative complications (chylothorax, respiratory infection and thoracic bleeding) and worsening of respiratory failure. We evaluated postoperative respiratory failure in five reintubated patients. Conclusion: Prolongated perioperative and postoperative procedures were significantly associated with postoperative complications, worsening of the general condition and prolonged postoperative treatment.
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    Tic disorder in the pediatric population
    (SHMSHM / AAMD, 2017)
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    Angelkova N
    Tics are defined as a recurrent, non-rhythmic series of movements, of a non-voluntary nature, in one or several muscle groups. Tics are sudden twitches, movements, or sounds that people do repeatedly. They can take place anywhere on the body and be very frequent. The lifetime prevalence of tic disorder is not known but estimates vary between 5% and 10% of the population, with estimations of 18% in child population. No definitive cause of tics has been discovered yet. Vulnerability to tic disorders seems to be genetic or to run within families, even though no single gene has been found. High rates of comorbid conditions are recognized in persons with tic disorders especially in patients with Tourette syndrome, like obsessive-compulsive disorder, attention-deficit/hyperactivity disorder and anxiety disorders. Currently, there is no one effective cure for tic disorders, but there are treatments that can help manage them. The therapeutic approach should be determent individually and conducted by multidisciplinary team.