Faculty of Medicine
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Item type:Publication, A BILIARY LEAK FROM DUCTS OF LUSCHKA AFTER LAPAROSCOPIC CHOLECYSTECTOMY - IMAGING FINDINGS(Department of Anaesthesia and Reanimation, Faculty of Medicine, “Ss. Cyril and Methodius” University in Skopje, R.N.Macedonia, 2025-05) ;Peneva, Elena ;Gjorgjioska, StefaniAcute cholecystitis is a condition which treatment usually involves surgery, and the most used is laparoscopic cholecystectomy. Bile leakage is a complication of laparoscopic cholecystectomy, often caused by injury to small aberrant bile ducts, such as the ducts of Luschka. We report a case of a 25-years-old female who was presented with abdominal pain five days after laparoscopic cholecystectomy. A CT scan and MRCP scan revealed a small bile collection in the gallbladder bed and the bile leakage was suspected. A laparoscopic revision was performed, during which a biliary collection was aspirated. Further exploration of the gallbladder fossa revealed an aberrant bile duct (duct of Luschka), smaller than 1mm, actively secreting bile. The duct was successfully closed, leading to resolution of the leakage. The ducts of Luschka are one of the most common causes of bile leakage after laparoscopic cholecystectomy. Generally, most of the diagnoses are determined post operatively as a result of the post-operative complications that arise. It is important to take into consideration the imaging reports whenever we have post cholecystectomy bile leakage. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Practicing opioid-free anesthesia for laparoscopic cholecystectomy opioid-free anesthesia(Centre for Evaluation in Education and Science (CEON/CEES), 2019) ;Toleska, Marija; ; ; Dimitrovski, AleksandarOpioid free anesthesia (OFA) is an anesthesiological technique, which uses non-opioid analgesics, such as paracetamol, dexamethasone, lidocaine, ketamine, and magnesium sulfate instead of opioids. In this case, the report about patient who after previous surgeries experienced opioid side effects is followed by a narrative review; we present the OFA method for laparoscopic cholecystectomy. Case report: We present a case of a 55-year-old woman with a history of controlled hypertension and asthma, planned for laparoscopic cholecystectomy. Previously she underwent two surgical interventions; bilateral radical mastectomy performed separately with a three year gap. Both anesthesias were complicated, postoperatively with nausea, vomiting, dizziness, and respiratory depression. Based on the previous postoperative complications, we hypothesized that nausea, vomiting, dizziness, and respiratory depression were caused by opioids, and we decided to perform OFA. Before the induction the patient received dexamethasone 8 mg and paracetamol 1 gr intravenously, followed by induction with midazolam 3 mg, lidocaine hydrochloride 78 mg, propofol 160 mg, ketamine hydrochloride 39 mg and rocuronium bromide 60 mg. After tracheal intubation, continuous intravenous infusion with lidocaine hydrochloride 2 mg/kg/hr and magnesium sulfate 1.5 gr/hr was started. Anesthesia was maintained by using sevoflurane MAC 0.7–1. At the end of the surgery, 2.5 gr of metamizole was given intravenously. Postoperative recovery was uneventful. Conclusion: In our patient, OFA eliminated opioid-related side effects (nausea, vomiting, dizziness, and shortness of breath), and provided satisfying postoperative analgesia. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, ACUTE APPENDICITIS ASSOCIATED WITH ENTEROBIUS VERMICULARIS –CASE REPORT(Македонско лекарско друштво = Macedonian medical association, 2020) ;Radomir Gelevski; ; ; Marija ToleskaEnterobius vermicularis, typically found in cecum, appendix or terminal ileum, is the cause of the most common helminthic infestation in humans. A 19-year-old female patient, with normal laboratory results, was admitted for urgent appendectomy via McBurney inci-sion. After ligation and division of the inflamed appendixfrom the cecal basis, several viable and mobile enterobiusvermiculareswere identified. A short course of alben-dazole treatment was initiated and was interrupted on the second day as a result of the strong anaphylactic reaction. Contrast enhanced CT of the abdomen iden-tified infundibulum of the gallbladder filled with iregu-larhyperdense liquid indicative for parasitic infestation. One month later, elective laparoscopic cholecystectomywas performed, and the removed gallbladder was sentfor parasitological evaluation confirming non-viable worms. Infestation with Enterobius vermicularisobstructsthe lumen of the appendix, causing contraction of the wall and results in appendicitis-like symptoms without signs of acute inflammation. In minority of cases, with pure pathological signs of inflammation a finding of Eneterobius vermicularisis incidental. There are two possible hypotheses regarding the exact mechanism of gallbladder involvement: hematogenous spread or directmigration through unhealthy intestinal tissue. It is recommended to thoroughly examine all appendiceal specimens for presence of this worm, in order to provideadequate anthelminthic therapy in case of infestation. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, DOUBLE, VERY SHORT CYSTIC ARTERY: ANATOMIC VARIATION REVEALED DURING LAPAROSCOPIC CHOLECYSTECTOMY: A CASE REPORT(Македонско лекарско друштво = Macedonian Medical Association, 2020); ; ; ;Marija ToleskaIntroduction. The cystic artery (CA) is the key struc-ture sought to be clipped or ligated during laparoscopicor conventional cholecystectomy.In up to 25% of sub-jects, the superficial and deep branches of the CA have separate origins and Michels called them double CA. Case report. We are presenting a 38-year-old female with one-year history of chronic gallbladder inflamma-tion. During the laparoscopy dissection in the region of the Calot’striangle, we revealed an anatomic va-riation of the cystic artery-a double cystic artery. The more important thing was that both branches were ex-tremely short, or at the lower limit of the publishedlengths of this blood vessel-approximately 3mm each. Bydoing so, the surgicalcourse further took the standardcourse-laparoscopic clips were placed on both branches. Conclusion. The incidence of double CA ranges from 15 to 25%. Such arteries usually arise from RHA and frequently replace the deep branch of the CA. Anatomicvariations in and around Calot’s triangle are frequent. Therefore, careful dissection of Calot’s triangle is ne-cessary for both conventional and laparoscopic chole-cystectomy. Hemorrhage could be a problem during search of the CA if these variations are overlooked and that increases the rate of conversion to open surgery. It also hasto be kept in mind that during laparoscopic visualization anatomical relations are seen differently compared to conventional cholecystectomy
