Faculty of Medicine

Permanent URI for this communityhttps://repository.ukim.mk/handle/20.500.12188/14

Browse

Settings

Subject: search.filters.subject.hospitalization

Search Results

Now showing 1 - 2 of 2
  • Loading...
    Thumbnail Image
    Some of the metrics are blocked by your 
    consent settings
    Item type:Publication,
    TROPONIN I VISOKE OSETLJIVOSTI I DUŽINA BORAVKA U BOLNICI KOD AKUTNO OTROVANIH PACIJENATA SA RABDOMIOLIZOM
    (2023-05)
    ;
    ;
    Niko Bekarovski
    ;
    Andon Chibishev
    ;
    Cardiac troponins (cTn) are regulatory proteins that play a pivotal role in the interaction between actin and myosin, controlling the contraction and relaxation of skeletal and cardiac muscle. The high-sensitivity cardiac troponin I assay is not entirely specific for myocardial injury. The aim is to determine the role of hs–TroponinI on the hospital length of stay in patients with rhabdomyolysis acutely intoxicated with psychotropic and chemical substances. In a clinically controlled prospective study, 140 patients with rhabdomyolysis were divided into two groups depending on the intoxicating substance (psychotropic or chemical). Rhabdomyolysis was defined as a creatine kinase (CK)>250 U/L according to the poisoning severity score (PSS). We analyze hs–TroponinI in both groups upon admission. In patients with rhabdomyolysis in the group of psychotropic intoxications, the level of hs-TnI on admission significantly affected the length of hospitalization in 17.7% (R2 = 0.177). Increasing the value of the hs-TnI level per unit on admission increased the length of hospital stay by an average of 0.016 days. In patients with rhabdomyolysis in the chemical intoxication group, the hs-TnI level on admission has no influence on the hospital length of stay (R2 = 0.000). The increased hs-TnI level on the first day did not affect the hospital length of stay variability. In patients with rhabdomyolysis acutely intoxicated with psychotropic substances, hs-Tn I can be used to predict the length of hospital stay
  • Loading...
    Thumbnail Image
    Some of the metrics are blocked by your 
    consent settings
    Item type:Publication,
    Endoscopic findings and emerging complications after ingestion of corrosive substances
    (GUARANT International spol. s r.o., 2021-12)
    ;
    ;
    ;
    ;
    Aim: To evaluate the most commonly ingested corrosive substance, endoscopic findings, complications and the final outcome of caustic intake. Methods: This cross sectional study covered 220 inpatient participants during a three years period (2017- 2019). Data from the National patient electronic system “My term” and from the “Poisoning information center” at University Clinic of Toxicology, Skopje were used. Demographic characteristics, type of corrosive substance, endoscopic findings – Kikendall classification, emerging complications, fatal outcome, and hospitalization were analyzed. Results: Out of 220 inpatient cases with corrosive substance intake, there were acids 60% (n=132), bases 8.6% (n=19), bleaches 14.5% (n=32) and other household products 16.8% (n=37). Patients which took acids/bases were significantly older compared to bleaches/other (p=0.0009). Hospitalization was significantly longer in base and acid ingestion compared to bleaches and other (p=0.0005). Upper gastrointestinal endoscopy was declined by 10% (n= 22) and 10% (n=22) of patients were with fatal outcome. The most severe endoscopy findings were in acid and base ingestion. Esophagus findings in acids -grade I (1.92%), grade IIA (50%), grade IIB (27%) and grade III (21.1%), in bases – grade IIA (7.2%), grade IIB (57.1%) and grade III (35.7%); Stomach findings in acids-grade I (2.9%), grade IIA (29.8%), grade IIB (37.5%), grade III (29.8%), in bases-grade IIA (13.4%), grade IIB (33.4%), grade III (53.2%); Duodenum findings in acids-grade I (62.5%), grade IIA (23.1%), grade IIB (14.4%), in bases-grade IIA (26.7%), grade IIB (40%), grade III (33.3%). In 22.2% (n=39) of cases were registered complications (strictures): esophagus 43.6% (n=17), stomach 25.7% (n=10), on both organs 30.8% (n=12). Conclusion: Corrosive substances result in serious injuries to the mucosa of the gastrointestinal tract, which are confirmed by endoscopic findings. These conditions are often accompanied by complications such as strictures and can lead to fatal outcomes as well.