Faculty of Medicine
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Item type:Publication, Video-assisted thoracic surgery (VATS) hybrid esophagectomy after neoadjuvant treatment – case report(2023-03-01); ;Igor Dzikovski ;Despot Despotovski ;Faik MisimiMarija SimonovskaEsophageal cancer is an aggressive malignancy. It is 6 th among the leading causes of cancer death and the 8 th most common cancer type worldwide. Regarding gender distribution, esophageal cancer is about 2–4 times more frequent among males than females. There are two main histological types; esophageal squamous cell carcinoma is typically localized in the upper- middle esophagus being the most frequent histological type and adenocarcinoma subtype, usually localized in the lower esophagus. Over the past two decades, video-assisted thoracic surgery (VATS) has revolutionized how thoracic surgeons diagnose and treat esophageal diseases. Because of the advancement of surgical laparoscopic and thoracoscopic procedures and endoscopic instrumentation, minimally invasive esophagectomy (MIE) is performed to enhance surgical outcomes and reduce surgical morbidity. Here, we present a case of, video-assisted thoracic surgery hybrid esophagectomy in a 63-year-old patient with esophageal cancer who had received neoadjuvant therapy. Surgical technique: the patient was first placed in the supine position under general anesthesia and double-lumen intubation. An upper median laparotomy was performed to mobilize and tubulate the stomach conduit. Then we continued with a left lateral decubitus position; 4 cm incision was made in the 5th intercostal space to accommodate the thoracoscopic instruments. The dissection and mobilization of the esophagus were carried out from the esophageal hiatus to the upper thoracic inlet after opening the posterior mediastinal pleura. After this step, the stomach conduit was pulled-up through the esophageal hiatus and laterolateral esophagogastric anastomosis was done in the chest. The postoperative course ended without complications, and the patient was discharged home on the 5th postoperative day. The, video-assisted thoracic surgery hybrid approach is an excellent option for esophageal cancer management, offering a quick recovery and low morbidity. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Open esophagectomy as a treatment of choice for esophageal cancerand a successful outcome at the University Clinic in Skopje, North Macedonia: a case report(University Ss. Cyril and Methodius, Medical Faculty in Skopje, 2022); ; ; ;Jakupi NKaragjozov PEsophageal cancer is one of the least studied cancers and has high mortality rates, mainly because it is diagnosed at rather late stage. It requires urgent attention and in patients where surgery is feasible, it is immediately performed. There is a considerable variation in terms of the surgical approach in different countries, but open esophagectomy is a treatment of choice. This study describes a case of esophageal squamous cell carcinoma that was successfully treated with open esophagectomy and therefore provides information about the present state of esophageal cancer surgery at the University Clinic in Skopje, North Macedonia. The patient underwent clinical examination after which she was admitted to our department for surgical treatment. Esophagography and CT imaging were done pre- and postoperatively and no complications were noted after surgery. The patient was discharged and a written informed consent was obtained for publication of this case and any accompanying images. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Esophageal, gastric, colorectal, pancreatic, hepatocellular carcinomas and cholangiocarcinomas in Northern Macedonia: A series of patients treated at the University Clinic, between 2015 and 2019(Centre for Evaluation in Education and Science (CEON/CEES), 2021); ; ;Stefanovski, Goran; <jats:p>Introduction: The global burden of gastrointestinal cancer (GIC) is growing. Stomach, colon and liver are among the five most common sites for GIC in men and women worldwide. The incidence of GIC shows significant variation in Europe and North America. Aim: The aim of this paper is to describe hospital morbidity from GI cancer at the University Clinic in Northern Macedonia. Materials and methods: A retrospective longitudinal analysis included a series of cases with GIC, at the University Clinic of Gastroenterohepatology (UCG) in Skopje, in the period 2015-2019. Descriptive statistical methods were used to describe hospital morbidity from GIC, and its distribution by age, sex, and cancer site. Results: In a five-year period, a total of 2,831 patients with GIC were treated at the UCG, of which 1,484 patients had colorectal cancer, 763 patients had gastric cancer and 88 patients had esophageal cancer. Although liver cancers were less common, as many as one eighth of such patients (355 or 13%) had nonspecific liver malignancy. Most patients were in the 60-69 age group, with the exception of esophageal cancer. An increase in the incidence of pancreatic cancer was observed, almost equal, when considering the distribution by sex, and mainly in the age groups 60-69 and 70-79 years. Conclusion: Hospital morbidity due to GIC in North Macedonia shows an increasing trend, so it is important to determine how much screening has contributed to the early detection of these cancers and to ensure access to and availability of therapy for hepatitis B and C.</jats:p>
