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Subject: search.filters.subject.atrial septal defect

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    Right bundle branch block as a marker for interatrial septal abnormalities
    (Cambridge University Press, 2012-02)
    Bakalli, A
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    Kocinaj, D
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    Bekteshi, T
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    Pilana, E
    Background: Interatrial septal anomalies, which include atrial septal defect, patent foramen ovale, and atrial septal aneurysm, are common disorders among adult patients. Early detection of interatrial septal anomalies is important in order to prevent haemodynamic consequences and/or thromboembolic events. Electrocardiogram offers some clues that should serve as hints for detection of interatrial abnormalities. The aim of our study was to analyse the interatrial septum by transoesophageal echocardiography in patients with electrocardiogram signs of right bundle branch block and in those without right bundle branch block. Methods and results: In a prospective study, 87 adult patients were included, that is, 41 with electrocardiogram signs of right bundle branch block forming the first group and 46 without right bundle branch block forming the second group. Interatrial septal anomalies were present in 80.5% of the patients with right bundle branch block, with patent foramen ovale (39.02%) being the most prevalent disorder, followed by atrial septal aneurysm (21.9%) and atrial septal defect (19.5%). Interatrial septal abnormalities were significantly more frequent in the first group compared with the second group (80.5% versus 6.5%, p value less than 0.001). Independently, patent foramen ovale was significantly more prevalent in patients with right bundle branch block (39.02% versus 4.3%, p value less than 0.001), as were atrial septal aneurysm (21.9% versus 2.2%, p value equal 0.01) and atrial septal defect (19.5% versus 0%, p value equal 0.004). Conclusions: Right bundle branch block should serve as a valuable indicator to motivate a detailed search for interatrial septal abnormalities.
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    Migraine association with atrial septal defect - a case report.
    (Macedonian Association of Anatomists, 2018)
    Ristikj, Daniela
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    Ristovski, Vladimir
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    Migraine belongs to the group of primary headaches, in whose pathogenesis, despite the involvement of neurovascular, significant part, has the genetic factors, as well.The prevalence of migraine with aura in patients with atrial septal defect ranges from 11-22%.We present a case of a patient at the age of 28, with persistent headaches,18 months backwards. Headaches were usually preceded byphosphenescence, blurred vision, buzzing in both ears, nausea, feeling of tingling of the right hemicranium.An incomplete hour later severe headaches appeared, followed by tingling and a feeling of weakness on the left arm and lower extremities.Neurological examination was with left sided paresthesias and hemiparesis.Routine biochemical examinations,hormone status, magnetic nuclear resonance of the brain and magnetic resonance angiography of intracranial vessels, cerebrospinal fluid analysis, and neurophysiological examinationswas normal.At the transthoracic, and then transoesophageal echocardiography, was proved the presence of Atrial septal defect (ASD) in the central part of the interatrial septum.In the patient, anocclusion of ASD with ASD occluder was made,there was a reduction in the frequency of occurrence of migraine headaches.Controlled echocardiography was performed where the absence of the pre-establishedASD occluder was observed in the aortic arch, wherethe removal of the dive (occlusion) was done and the closing of the ASD with a direct suture.A pathogenetic mechanism that explains the association of ASD / PFO with migraine is interatrial communication, which may result in the occurrence of paradoxicalembolismand humoral factorsof the pulmonary circulation